Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …

Pathogenesis of autoimmune disease

DS Pisetsky - Nature Reviews Nephrology, 2023 - nature.com
Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and …

Kidney biopsy findings in patients with COVID-19

S Kudose, I Batal, D Santoriello, K Xu… - Journal of the …, 2020 - journals.lww.com
Background Coronavirus disease 2019 (COVID-19) is thought to cause kidney injury by a
variety of mechanisms. To date, pathologic analyses have been limited to patient reports …

IgG4-related disease

T Kamisawa, Y Zen, S Pillai, JH Stone - The Lancet, 2015 - thelancet.com
IgG4-related disease is a protean condition that mimics many malignant, infectious, and
inflammatory disorders. This multi-organ immune-mediated condition links many disorders …

Evolving importance of kidney disease: from subspecialty to global health burden

KU Eckardt, J Coresh, O Devuyst, RJ Johnson… - The Lancet, 2013 - thelancet.com
In the past decade, kidney disease diagnosed with objective measures of kidney damage
and function has been recognised as a major public health burden. The population …

Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy

NM Tomas, LH Beck Jr… - … England Journal of …, 2014 - Mass Medical Soc
Background Idiopathic membranous nephropathy is an autoimmune disease. In
approximately 70% of patients, it is associated with autoantibodies against the …

Primary membranous nephropathy

WG Couser - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …

Discovery of autoantibodies targeting nephrin in minimal change disease supports a novel autoimmune etiology

AJB Watts, KH Keller, G Lerner, I Rosales… - Journal of the …, 2022 - journals.lww.com
Background Failure of the glomerular filtration barrier, primarily by loss of slit diaphragm
architecture, underlies nephrotic syndrome in minimal change disease. The etiology …

[HTML][HTML] Overview of complement activation and regulation

M Noris, G Remuzzi - Seminars in nephrology, 2013 - Elsevier
Complement is an important component of the innate immune system that is crucial for
defense from microbial infections and for clearance of immune complexes and injured cells …

Glomerulonephritis: immunopathogenesis and immunotherapy

HJ Anders, AR Kitching, N Leung… - Nature Reviews …, 2023 - nature.com
Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …