Background Scrub typhus is a vector-borne zoonotic disease that can be life-threatening.
There are no licensed vaccines, or vector control efforts in place. Despite increasing …

Background Scrub typhus, a bacterial infection caused by Orientia tsutsugamushi, is
increasingly recognized as an important cause of fever in Asia, with an estimated one million …

Scrub typhus is a life-threatening zoonosis caused by Orientia tsutsugamushi organisms that
are transmitted by the larvae of trombiculid mites. Endemic scrub typhus was originally …

Introduction: Doxycycline is highly effective, inexpensive with a broad therapeutic spectrum
and exceptional bioavailability. However these benefits have been overshadowed by its …

Leptospirosis is a widespread bacterial zoonosis with highest burden in low-income
populations living in tropical and subtropical regions, both in urban and in rural …

Background Leptospirosis is a common zoonoses and is a major global public health threat.
Most cases are mild, typically presenting as a non-specific acute febrile illness. However …

Many bacterial infections are major health problems worldwide, and treatment of many of
these infectious diseases is becoming increasingly difficult due to the development of …

As a result of migrations and globalization, people may face a possible increase in the
incidence of central nervous system rickettsial infections (CNS R). These diseases, caused …

Scrub typhus is an established cause of acute encephalitis syndrome (AES) in northern
states of India. We systematically investigated 376 children with AES in southern India, using …

Background Encephalitis is a worldwide public health issue, with a substantially high burden
among children in southeast Asia. We aimed to determine the causes of encephalitis in …