BoLA-DRB3 polymorphism is associated with differential susceptibility to bovine leukemia virus-induced lymphoma and proviral load

CW Lo, L Borjigin, S Saito, K Fukunaga, E Saitou… - Viruses, 2020 - mdpi.com
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. However,
less than 5% of BLV-infected cattle will develop lymphoma, suggesting that, in addition to …

[PDF][PDF] Association of BoLA-DRB3 with bovine leukemia virus

CW Lo, Y Aida - MHC, 2022 - jshi.umin.ac.jp
The major histocompatibility complex (MHC) of cattle is known as BoLA and located on
chromosome 23. It was found that BoLA shows significant differences in genome …

[HTML][HTML] Estimation of genetic parameters and genome-wide association study for enzootic bovine leukosis resistance in Canadian Holstein cattle

R Bongers, CM Rochus, K Houlahan, C Lynch… - Journal of Dairy …, 2025 - Elsevier
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (hereafter
referred to as leukosis), frequently observed in North American dairy herds. Infection with …

A pooled testing system to rapidly identify cattle carrying the elite controller BoLA‐DRB3*009:02 haplotype against bovine leukemia virus infection

K Notsu, H El Daous, S Mitoma, J Norimine… - Hla, 2022 - Wiley Online Library
As genetically resistant individuals, the “elite controllers”(ECs) of human immunodeficiency
virus infection have been focused on as the keys to develo** further functional treatments …

BoLA-DRB3 Polymorphism Associated with Bovine Leukemia Virus Infection and Proviral Load in Holstein Cattle in Egypt

R Hamada, S Metwally, R Matsuura, L Borjigin, CW Lo… - Pathogens, 2023 - mdpi.com
Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leukosis, the most
prevalent neoplastic disease of cattle worldwide. The immune response to BLV and disease …

[HTML][HTML] First characterization of major histocompatibility complex class II DRB3 diversity in cattle breeds raised in Egypt

R Hamada, G Giovambattista, S Metwally, L Borjigin… - Gene, 2024 - Elsevier
Genes encoding bovine leukocyte antigen (BoLA) enable the immune system to identify
pathogens. Therefore, these genes have been used as genetic markers for infectious and …

Association between BoLA‐DRB3 polymorphism and bovine leukemia virus proviral load in Vietnamese Holstein Friesian cattle

TD Le, VS Nguyen, CW Lo, DT Dao, NV Bui, H Ogawa… - Hla, 2022 - Wiley Online Library
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis.
Polymorphism in bovine leukocyte antigen (BoLA)‐DRB3 allele can influence the host …

Identifying pathogen and allele type simultaneously in a single well using droplet digital PCR

K Notsu, H El Daous, S Mitoma, X Wu, J Norimine… - Msphere, 2023 - Am Soc Microbiol
In the transmission control of chronic and untreatable livestock diseases such as bovine
leukemia virus (BLV) infection, the removal of viral superspreaders is a fundamental …

The influence of risk factors on bovine leukemia virus infection and proviral load in egyptian cattle

R Hamada, RM Fereig, S Metwally - Veterinary Research …, 2024 - Springer
Bovine leukemia virus (BLV) is the etiological agent of enzootic bovine leucosis (EBL),
which affects cattle globally. In Egypt, BLV control strategies have been ignored because of …

[PDF][PDF] Association of BoLA-DRB3. 2 alleles with enzootic bovine leukosis: profiles BLV infection, persistent lymphocytosis and antibody production in Harton del Valle …

D Hernandez, D Montes, LA Alvarez - Indian Journal of Science and …, 2018 - academia.edu
Abstract Objectives: To associate the BoLA-DRB3 alleles with the resistance and/or
susceptibility to the development of the Enzootic Bovine Leukosis (EBL), in the Harton del …