Dual role of indoles derived from intestinal microbiota on human health

X Ye, H Li, K Anjum, X Zhong, S Miao, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Endogenous indole and its derivatives (indoles), considered as promising N-substituted
heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and …

Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action

R Roy, M Tiwari, G Donelli, V Tiwari - Virulence, 2018 - Taylor & Francis
Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

Biofilm formation and inhibition mediated by bacterial quorum sensing

Y Wang, Z Bian, Y Wang - Applied Microbiology and Biotechnology, 2022 - Springer
As a complex microbial aggregate, biofilm is a group behavior of bacterial ability to adapt to
the environment. Bacteria produce biofilm substrates that enhance their tolerance to stress …

Engineered living materials: prospects and challenges for using biological systems to direct the assembly of smart materials

PQ Nguyen, NMD Courchesne… - Advanced …, 2018 - Wiley Online Library
Vast potential exists for the development of novel, engineered platforms that manipulate
biology for the production of programmed advanced materials. Such systems would possess …

Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

ZH Zhao, FZ **n, Y Xue, Z Hu, Y Han, F Ma… - … & Molecular Medicine, 2019 - nature.com
Microbial metabolites have emerged as critical components that mediate the metabolic
effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan …

Microbiome, metabolites and host immunity

M Levy, E Blacher, E Elinav - Current opinion in microbiology, 2017 - Elsevier
Highlights•The gut encompasses thousands of small metabolites, collectively termed the
metabolome.•The metabolome is contributed by diet, the host, and its microbiome.•Multiple …

Roles of indole as an interspecies and interkingdom signaling molecule

JH Lee, TK Wood, J Lee - Trends in microbiology, 2015 - cell.com
A number of bacteria, and some plants, produce large quantities of indole, which is
widespread in animal intestinal tracts and in the rhizosphere. Indole, as an interspecies and …

Bacterial persister cell formation and dormancy

TK Wood, SJ Knabel, BW Kwan - Applied and environmental …, 2013 - Am Soc Microbiol
Bacterial cells may escape the effects of antibiotics without undergoing genetic change;
these cells are known as persisters. Unlike resistant cells that grow in the presence of …

Role of bacterial volatile compounds in bacterial biology

B Audrain, MA Farag, CM Ryu… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial interactions with neighboring microorganisms via production of small metabolites
enable bacteria to respond and adapt to environmental changes. The study of intercellular …

Auxin and plant-microbe interactions

S Spaepen, J Vanderleyden - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Microbial synthesis of the phytohormone auxin has been known for a long time. This
property is best documented for bacteria that interact with plants because bacterial auxin …