Vascular endothelial growth factor (VEGF) is an apparently endothelial cell-specific mitogen
that is structurally related to platelet-derived growth factor. By Northern blot and protein …

Tumor-promoting phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA)
directly activate in vitro Ca2+-activated, phospholipid-dependent protein kinase (protein …

The worldwide importance of human hepatitis B virus infection and the toll it takes in chronic
liver disease, cirrhosis and hepatocarcinoma, make it imperative that a vaccine be …

We have characterized a new selenium-dependent glutathione peroxidase, GSHPx-GI, by
expressing a GSHPx-GI cDNA isolated from human hepatoma HepG2 cells in human …

Homologous or agonist-specific desensitization of beta 2-adrenergic receptors (beta 2AR) is
mediated by the beta-adrenergic receptor kinase (beta ARK) which specifically …

ATP-dependent calcium pumps that reside in intracellular organelles are encoded by a
family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum Ca …

The phosphotriesterase produced from the opd cistron of Pseudomonas diminuta was
purified 1500-fold to homogeneity using a combination of gel filtration, ion exchange …

Previously our laboratory reported the discovery of a novel protein-saccharide linkage in
which single N-acetylglucosamine (GlcNAc) residues are attached in O-linkages to protein …

The transport of precursor proteins into mitochondria requires an energized inner
membrane. We report here that the import of various precursor proteins showed a differential …

Thioredoxin, despite its function as an intracellular disulfide reducing enzyme and its lack of
a signal sequence, has been found to play some roles extracellularly. Here we show that …