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A size-dependent division strategy accounts for leukemia cell size heterogeneity
Heterogeneity in the size distribution of cancer cell populations is linked to drug resistance
and invasiveness. However, understanding how such heterogeneity arises is still damped …
and invasiveness. However, understanding how such heterogeneity arises is still damped …
Cell size distribution of lineage data: analytic results and parameter inference
Recent advances in single-cell technologies have enabled time-resolved measurements of
the cell size over several cell cycles. These data encode information on how cells correct …
the cell size over several cell cycles. These data encode information on how cells correct …
A population-based approach to study the effects of growth and division rates on the dynamics of cell size statistics
N Totis, C Nieto, A Küper… - IEEE Control …, 2020 - ieeexplore.ieee.org
The dynamics of the size distribution in growing and dividing rod-shaped bacteria can
change depending on the perspective through which the cell population is observed. From …
change depending on the perspective through which the cell population is observed. From …
Pyecolib: a python library for simulating stochastic cell size dynamics
Recently, there has been an increasing need for tools to simulate cell size regulation due to
important applications in cell proliferation and gene expression. However, implementing the …
important applications in cell proliferation and gene expression. However, implementing the …
Feedbacks between size and density determine rapid eco‐phenotypic dynamics
Body size is a fundamental trait linked to many ecological processes—from individuals to
ecosystems. Although the effects of body size on metabolism are well‐known, the potential …
ecosystems. Although the effects of body size on metabolism are well‐known, the potential …
Stochastic chemical kinetics of cell fate decision systems: From single cells to populations and back
Stochastic chemical kinetics is a widely used formalism for studying stochasticity of chemical
reactions inside single cells. Experimental studies of reaction networks are generally …
reactions inside single cells. Experimental studies of reaction networks are generally …
Characterizing non-exponential growth and bimodal cell size distributions in fission yeast: An analytical approach
Unlike many single-celled organisms, the growth of fission yeast cells within a cell cycle is
not exponential. It is rather characterized by three distinct phases (elongation, septation, and …
not exponential. It is rather characterized by three distinct phases (elongation, septation, and …
Coupling cell size regulation and proliferation dynamics of C. glutamicum reveals cell division based on surface area
Single cells actively coordinate growth and division to regulate their size, yet how this size
homeostasis at the single-cell level propagates over multiple generations to impact clonal …
homeostasis at the single-cell level propagates over multiple generations to impact clonal …
Continuous rate modeling of bacterial stochastic size dynamics
Bacterial division is an inherently stochastic process with effects on fluctuations of protein
concentration and phenotype variability. Current modeling tools for the stochastic short-term …
concentration and phenotype variability. Current modeling tools for the stochastic short-term …
Cell size control shapes fluctuations in colony population
Exponentially growing cells regulate their size by controlling their timing of division. Since
two daughter cells are born as a result of this cell splitting, cell size regulation has a direct …
two daughter cells are born as a result of this cell splitting, cell size regulation has a direct …