Muscle wasting in cancer
Skeletal muscle loss appears to be the most significant clinical event in cancer cachexia and
is associated with a poor outcome. With regard to such muscle loss, despite extensive study …
is associated with a poor outcome. With regard to such muscle loss, despite extensive study …
Targeting the cytoskeleton against metastatic dissemination
C Ruggiero, E Lalli - Cancer and Metastasis Reviews, 2021 - Springer
Cancer is a pathology characterized by a loss or a perturbation of a number of typical
features of normal cell behaviour. Indeed, the acquisition of an inappropriate migratory and …
features of normal cell behaviour. Indeed, the acquisition of an inappropriate migratory and …
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia–can findings from animal models be translated to humans?
TC Mueller, J Bachmann, O Prokopchuk, H Friess… - BMC cancer, 2016 - Springer
Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential
S Inaba, A Hinohara, M Tachibana, K Tsujikawa… - PloS one, 2018 - journals.plos.org
Cancer cachexia is a severe, debilitating condition characterized by progressive body
wasting associated with remarkable loss of skeletal muscle weight. It has been reported that …
wasting associated with remarkable loss of skeletal muscle weight. It has been reported that …
[HTML][HTML] Myosins as fundamental components during tumorigenesis: diverse and indispensable
YR Li, WX Yang - Oncotarget, 2016 - ncbi.nlm.nih.gov
Myosin is a kind of actin-based motor protein. As the crucial functions of myosin during
tumorigenesis have become increasingly apparent, the profile of myosin in the field of …
tumorigenesis have become increasingly apparent, the profile of myosin in the field of …
Down-regulated MYH11 expression correlates with poor prognosis in stage II and III colorectal cancer
RJ Wang, P Wu, GX Cai, ZM Wang, Y Xu… - Asian Pacific Journal …, 2014 - koreascience.kr
The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and
signal transduction. However, its relationship with prognosis is still uncertain. The aim of this …
signal transduction. However, its relationship with prognosis is still uncertain. The aim of this …
Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits
Introduction Physical health and function depend upon both genetic inheritance and
environmental factors (eg, exercise training). Purpose To enhance the understanding of …
environmental factors (eg, exercise training). Purpose To enhance the understanding of …
Spontaneous physical activity downregulates Pax7 in cancer cachexia
Emerging evidence suggests that the muscle microenvironment plays a prominent role in
cancer cachexia. We recently showed that NF‐kB‐induced Pax7 overexpression impairs the …
cancer cachexia. We recently showed that NF‐kB‐induced Pax7 overexpression impairs the …
Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients
A Anoveros‐Barrera, AS Bhullar… - Journal of cachexia …, 2019 - Wiley Online Library
Background Researchers increasingly use intraoperative muscle biopsy to investigate
mechanisms of skeletal muscle atrophy in patients with cancer. Muscles have been …
mechanisms of skeletal muscle atrophy in patients with cancer. Muscles have been …
Skeletal muscle regeneration in cancer cachexia
Muscle wasting is the most important phenotypic and clinical feature of cancer cachexia, and
the principal cause of impaired physical function, fatigue, and respiratory complications …
the principal cause of impaired physical function, fatigue, and respiratory complications …