Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions

B Mészáros, A Hatos, N Palopoli, F Quaglia… - Nature …, 2023 - nature.com
An unambiguous description of an experiment, and the subsequent biological observation,
is vital for accurate data interpretation. Minimum information guidelines define the …

DichroWeb, a website for calculating protein secondary structure from circular dichroism spectroscopic data

AJ Miles, SG Ramalli, BA Wallace - Protein Science, 2022 - Wiley Online Library
Circular dichroism (CD) spectroscopy is a widely‐used method for characterizing the
secondary structures of proteins. The well‐established and highly used analysis website …

MobiDB: 10 years of intrinsically disordered proteins

D Piovesan, A Del Conte, D Clementel… - Nucleic acids …, 2023 - academic.oup.com
The MobiDB database (URL: https://mobidb. org/) is a knowledge base of intrinsically
disordered proteins. MobiDB aggregates disorder annotations derived from the literature …

MobiDB: intrinsically disordered proteins in 2021

D Piovesan, M Necci, N Escobedo… - Nucleic acids …, 2021 - academic.oup.com
The MobiDB database (URL: https://mobidb. org/) provides predictions and annotations for
intrinsically disordered proteins. Here, we report recent developments implemented in …

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins

T Lazar, E Martínez-Pérez, F Quaglia… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Protein Ensemble Database (PED)(https://proteinensemble. org), which holds
structural ensembles of intrinsically disordered proteins (IDPs), has been significantly …

DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation

F Quaglia, B Mészáros, E Salladini, A Hatos… - Nucleic acids …, 2022 - academic.oup.com
Abstract The Database of Intrinsically Disordered Proteins (DisProt, URL: https://disprot. org)
is the major repository of manually curated annotations of intrinsically disordered proteins …

MOBIDB in 2025: integrating ensemble properties and function annotations for intrinsically disordered proteins

D Piovesan, A Del Conte, M Mehdiabadi… - Nucleic Acids …, 2025 - academic.oup.com
The MobiDB database (URL: https://mobidb. org/) aims to provide structural and functional
information about intrinsic protein disorder, aggregating annotations from the literature …

The PCDDB (protein circular dichroism data bank): a bioinformatics resource for protein characterisations and methods development

SG Ramalli, AJ Miles, RW Janes, BA Wallace - Journal of Molecular Biology, 2022 - Elsevier
Abstract The Protein Circular Dichroism Data Bank (PCDDB)[https://pcddb. cryst. bbk. ac. uk]
is an established resource for the biological, biophysical, chemical, bioinformatics, and …

DichroPipeline: A suite of online and downloadable tools and resources for protein circular dichroism spectroscopic data analyses, interpretations, and their …

RW Janes, BA Wallace - Protein Science, 2023 - Wiley Online Library
Circular Dichroism (CD) spectroscopy is a widely‐used method for characterizing individual
protein structures in solutions, membranes, films and macromolecular complexes, as well as …

Intrinsic disorder and flexibility in proteins: a challenge for structural biology and drug design

G Zanotti - Crystallography Reviews, 2023 - Taylor & Francis
The structure–function paradigm, ie the concept that it is the three-dimensional structure of a
protein that determines its function, has been partially modified by the discovery that a …