Oxidative stress and male infertility
T Takeshima, K Usui, K Mori, T Asai… - Reproductive …, 2021 - Wiley Online Library
Abstract Background Between 30% and 80% of patients with male infertility produce
excessive reactive oxygen species (ROS) in their ejaculate even though the cause of male …
excessive reactive oxygen species (ROS) in their ejaculate even though the cause of male …
Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring
Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …
the first child is conceived, either due to increased life expectancy, widespread use of …
Protamines and male infertility
R Oliva - Human reproduction update, 2006 - academic.oup.com
Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …
Impact of advanced paternal age on fertility and risks of genetic disorders in offspring
The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …
owing to various variables, including a longer life expectancy, more access to contraception …
The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy
P Gharagozloo, RJ Aitken - Human reproduction, 2011 - academic.oup.com
Oxidative stress in the male germ line is thought to affect male fertility and impact upon
normal embryonic development. Accordingly, fertility specialists are actively exploring the …
normal embryonic development. Accordingly, fertility specialists are actively exploring the …
Cryopreservation-induced human sperm DNA damage is predominantly mediated by oxidative stress rather than apoptosis
BACKGROUND Whereas studies have revealed that the cryopreservation of human semen
increases sperm DNA fragmentation, the mechanisms involved in this type of cryo-injury are …
increases sperm DNA fragmentation, the mechanisms involved in this type of cryo-injury are …
Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …
Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?
BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …
fertilization. This population is a selected group of cells since only motile cells can pass …
[HTML][HTML] Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
Sperm DNA damage in male infertility: etiologies, assays, and outcomes
RT Schulte, DA Ohl, M Sigman, GD Smith - Journal of assisted …, 2010 - Springer
Male factor infertility is the sole cause of infertility in approximately 20% of infertile couples,
with an additional 30% to 40% secondary to both male and female factors. Current means of …
with an additional 30% to 40% secondary to both male and female factors. Current means of …