Obesity and overweight have increased at an alarming rate in the world during the last three
decades. Obesity is a crucial factor in the development of metabolic abnormalities, including …

Obesity as an independent risk factor for cardiovascular diseases (CVDs) leads to an
increase in morbidity, mortality, and a shortening of life span. The changes in heart structure …

Tumor microenvironment (TME) formation is a major cause of immunosuppression. The TME
consists of a considerable number of macrophages and stromal cells that have been …

Adipocytokines are hormonally active molecules that are believed to play a key role in the
regulation of crucial biological processes in the human body. Numerous experimental …

The metabolic syndrome (MetS) comprises cardiometabolic risk factors frequently found in
individuals with obesity. Guidelines to prevent or reverse MetS suggest limiting fat intake …

Adiponectin (ADIPO) and interleukin-8 (IL-8) are proteins that play a significant, albeit
opposing, role in metabolic syndrome (MetS). The reported data on the effect of physical …

Obesity is associated with metabolic disorders such as insulin resistance and type 2
diabetes mellitus (T2DM), further increasing an already heightened cardiovascular risk …

Pregnancies affected by obesity are at high risk for develo** metabolic complications with
oxidative stress and adipocyte dysfunction contributing to the underlying pathologies. Few …

Abstract Background/Objectives Regular exercise such as aerobic exercise has been shown
to reduce the risk of some diseases such as cardiovascular disease (CVD). However, only …

Adipocytes and adipose tissue are not inert and make substantial contributions to systemic
metabolism by influencing energy homeostasis, insulin sensitivity, and lipid storage. In …