MAPK signal pathways in the regulation of cell proliferation in mammalian cells
W Zhang, HT Liu - Cell research, 2002 - nature.com
ABSTRACT MAPK families play an important role in complex cellular programs like
proliferation, differentiation, development, transformation, and apoptosis. At least three …
proliferation, differentiation, development, transformation, and apoptosis. At least three …
The MAPK signaling cascade
R Seger, EG Krebs - The FASEB journal, 1995 - Wiley Online Library
The transmission of extracellular signals into their intracellular targets is mediated by a
network of interacting proteins that regulate a large number of cellular processes …
network of interacting proteins that regulate a large number of cellular processes …
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
▪ Abstract Eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that mediates
recruitment of ribosomes to mRNA. This event is the rate-limiting step for translation under …
recruitment of ribosomes to mRNA. This event is the rate-limiting step for translation under …
Signal transduction through MAP kinase cascades
TS Lewis, PS Shapiro, NG Ahn - Advances in cancer research, 1998 - Elsevier
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1-to S-phase transition
The Ras-dependent extracellular signal-regulated kinase (ERK) 1/2 mitogen-activated
protein (MAP) kinase pathway plays a central role in cell proliferation control. In normal cells …
protein (MAP) kinase pathway plays a central role in cell proliferation control. In normal cells …
MKK3-and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
J Raingeaud, AJ Whitmarsh, T Barrett… - … and cellular biology, 1996 - Taylor & Francis
The p38 mitogen-activated protein (MAP) kinase signal transduction pathway is activated by
proinflammatory cytokines and environmental stress. The detection of p38 MAP kinase in the …
proinflammatory cytokines and environmental stress. The detection of p38 MAP kinase in the …
Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
A signaling pathway has been elucidated whereby growth factors activate the transcription
factor cyclic adenosine monophosphate response element-binding protein (CREB), a critical …
factor cyclic adenosine monophosphate response element-binding protein (CREB), a critical …
[HTML][HTML] Mitogen‐activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
Mitogen‐activated protein (MAP) kinases bind tightly to many of their physiologically
relevant substrates. We have identified a new subfamily of murine serine/threonine kinases …
relevant substrates. We have identified a new subfamily of murine serine/threonine kinases …
The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions
Y Keshet, R Seger - MAP Kinase Signaling Protocols: Second Edition, 2010 - Springer
Sequential activation of kinases within the mitogen-activated protein (MAP) kinase (MAPK)
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
LM Luttrell, FL Roudabush, EW Choy… - Proceedings of the …, 2001 - National Acad Sciences
Using both confocal immunofluorescence microscopy and biochemical approaches, we
have examined the role of β-arrestins in the activation and targeting of extracellular signal …
have examined the role of β-arrestins in the activation and targeting of extracellular signal …