CRISPR beyond: harnessing compact RNA-guided endonucleases for enhanced genome editing
The CRISPR-Cas system, an adaptive immunity system in prokaryotes designed to combat
phages and foreign nucleic acids, has evolved into a groundbreaking technology enabling …
phages and foreign nucleic acids, has evolved into a groundbreaking technology enabling …
[HTML][HTML] Research Progress and Application of Miniature CRISPR-Cas12 System in Gene Editing
Q Xuan, J Wang, Y Nie, C Fang, W Liang - International Journal of …, 2024 - mdpi.com
CRISPR-Cas system, a natural acquired immune system in prokaryotes that defends against
exogenous DNA invasion because of its simple structure and easy operation, has been …
exogenous DNA invasion because of its simple structure and easy operation, has been …
Have a Little Heart (or Not): Highly Minimized Skeletal Muscle Regulatory Cassettes with Low or No Activity in the Heart
CL Himeda, TI Jones, PL Jones - Human Gene Therapy, 2024 - liebertpub.com
Adeno-associated virus-mediated gene therapies for certain muscle disorders require
regulatory cassettes that provide high-level, striated muscle-specific activity. However …
regulatory cassettes that provide high-level, striated muscle-specific activity. However …
[CITAS][C] Tiny CRISPR molecular switch tool opens a new world
Y Oh, SH Lee - Molecular Therapy, 2024 - cell.com
In recent years, the CRISPR-Cas9 system, which has been applied in various living systems
to cut a target gene and induce reprogrammed gene editing, has gained considerable …
to cut a target gene and induce reprogrammed gene editing, has gained considerable …