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Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature
Various parental characteristics, including psychiatric disorders and parenting behaviours,
are associated with offspring mental health and related outcomes in observational studies …
are associated with offspring mental health and related outcomes in observational studies …
Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes
JB **ault, AG Allegrini, T Odigie… - Journal of Child …, 2022 - Wiley Online Library
Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …
exposures typically classified as environmental have been found to be heritable. A …
Twins and causal inference: leveraging nature's experiment
TA McAdams, FV Rijsdijk… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
In this review, we discuss how samples comprising monozygotic and dizygotic twin pairs can
be used for the purpose of strengthening causal inference by controlling for shared …
be used for the purpose of strengthening causal inference by controlling for shared …
Annual research review: Towards a deeper understanding of nature and nurture: Combining family‐based quasi‐experimental methods with genomic data
TA McAdams, R Cheesman… - Journal of Child …, 2023 - Wiley Online Library
Distinguishing between the effects of nature and nurture constitutes a major research goal
for those interested in understanding human development. It is known, for example, that …
for those interested in understanding human development. It is known, for example, that …
[HTML][HTML] Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms
ES Jami, AR Hammerschlag, HF Ip, AG Allegrini… - Journal of the American …, 2022 - Elsevier
Objective To investigate the genetic architecture of internalizing symptoms in childhood and
adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies …
adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies …
Annual Research Review:'There, the dance is–at the still point of the turning world'–dynamic systems perspectives on coregulation and dysregulation during early …
S Wass, E Greenwood, G Esposito… - Journal of Child …, 2024 - Wiley Online Library
During development we transition from coregulation (where regulatory processes are
shared between child and caregiver) to self‐regulation. Most early coregulatory interactions …
shared between child and caregiver) to self‐regulation. Most early coregulatory interactions …
[HTML][HTML] Systematic review and meta-analysis of genetically informed research: associations between parent anxiety and offspring internalizing problems
Objective Parent anxiety is associated with offspring internalizing problems (emotional
problems related to anxiety and depression). This may reflect causal processes, whereby …
problems related to anxiety and depression). This may reflect causal processes, whereby …
Why we need families in genomic research on developmental psychopathology
Background Fundamental questions about the roles of genes, environments, and their
interplay in developmental psychopathology have traditionally been the domain of twin and …
interplay in developmental psychopathology have traditionally been the domain of twin and …
[HTML][HTML] Maternal depression and the polygenic p factor: A family perspective on direct and indirect effects
Within-family studies typically assess indirect genetic effects of parents on children, however
social support theory points to a critical role of partners and children on women's …
social support theory points to a critical role of partners and children on women's …
Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems
Anxiety and depression (emotional disorders) are familial and heritable, especially when
onset is early. However, other cross-generational studies suggest transmission of youth …
onset is early. However, other cross-generational studies suggest transmission of youth …