Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature

ES Jami, AR Hammerschlag, M Bartels… - Translational …, 2021 - nature.com
Various parental characteristics, including psychiatric disorders and parenting behaviours,
are associated with offspring mental health and related outcomes in observational studies …

Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes

JB **ault, AG Allegrini, T Odigie… - Journal of Child …, 2022 - Wiley Online Library
Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …

Twins and causal inference: leveraging nature's experiment

TA McAdams, FV Rijsdijk… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
In this review, we discuss how samples comprising monozygotic and dizygotic twin pairs can
be used for the purpose of strengthening causal inference by controlling for shared …

Annual research review: Towards a deeper understanding of nature and nurture: Combining family‐based quasi‐experimental methods with genomic data

TA McAdams, R Cheesman… - Journal of Child …, 2023 - Wiley Online Library
Distinguishing between the effects of nature and nurture constitutes a major research goal
for those interested in understanding human development. It is known, for example, that …

[HTML][HTML] Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms

ES Jami, AR Hammerschlag, HF Ip, AG Allegrini… - Journal of the American …, 2022 - Elsevier
Objective To investigate the genetic architecture of internalizing symptoms in childhood and
adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies …

Annual Research Review:'There, the dance is–at the still point of the turning world'–dynamic systems perspectives on coregulation and dysregulation during early …

S Wass, E Greenwood, G Esposito… - Journal of Child …, 2024 - Wiley Online Library
During development we transition from coregulation (where regulatory processes are
shared between child and caregiver) to self‐regulation. Most early coregulatory interactions …

[HTML][HTML] Systematic review and meta-analysis of genetically informed research: associations between parent anxiety and offspring internalizing problems

YI Ahmadzadeh, T Schoeler, M Han, JB **ault… - Journal of the American …, 2021 - Elsevier
Objective Parent anxiety is associated with offspring internalizing problems (emotional
problems related to anxiety and depression). This may reflect causal processes, whereby …

Why we need families in genomic research on developmental psychopathology

R Cheesman, Z Ayorech, EM Eilertsen… - JCPP …, 2023 - Wiley Online Library
Background Fundamental questions about the roles of genes, environments, and their
interplay in developmental psychopathology have traditionally been the domain of twin and …

[HTML][HTML] Maternal depression and the polygenic p factor: A family perspective on direct and indirect effects

Z Ayorech, R Cheesman, EM Eilertsen… - Journal of Affective …, 2023 - Elsevier
Within-family studies typically assess indirect genetic effects of parents on children, however
social support theory points to a critical role of partners and children on women's …

Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems

A Shakeshaft, J Martin, CA Dennison, L Riglin… - Molecular …, 2024 - nature.com
Anxiety and depression (emotional disorders) are familial and heritable, especially when
onset is early. However, other cross-generational studies suggest transmission of youth …