Fisetin—In search of better bioavailability—From macro to nano modifications: A review

J Szymczak, J Cielecka-Piontek - International Journal of Molecular …, 2023 - mdpi.com
As secondary plant metabolites, polyphenols are abundant in fruits and vegetables. They
are in high demand because of their many health benefits. However, their low bioavailability …

Gel formulations for topical treatment of skin cancer: a review

M Slavkova, B Tzankov, T Popova, C Voycheva - Gels, 2023 - mdpi.com
Skin cancer, with all its variations, is the most common type of cancer worldwide.
Chemotherapy by topical application is an attractive strategy because of the ease of …

Design-of-experiment-assisted fabrication of biodegradable polymeric nanoparticles: in vitro characterization, biological activity, and in vivo assessment

MA Mir, MH Akhter, O Afzal, SO Rab, ASA Altamimi… - ACS …, 2023 - ACS Publications
Berberine (BER) is an alkaloid obtained from berberis plant having broad biological
activities including anticancer. BER-encapsulated alginate (ALG)/chitosan (CHS) …

Natural oils enhance the topical delivery of ketoconazole by nanoemulgel for fungal infections

I Ahmad, M Farheen, A Kukreti, O Afzal, MH Akhter… - ACS …, 2023 - ACS Publications
Nanoemulgel (NEG) pharmaceutical formulations are gaining popularity because of their
ability to serve both as a nanoemulsion and as a gel. These products are well-known for …

A β–Sitosterol encapsulated biocompatible alginate/chitosan polymer nanocomposite for the treatment of breast Cancer

O Afzal, MH Akhter, I Ahmad, K Muzammil, A Dawria… - Pharmaceutics, 2022 - mdpi.com
β–sitosterol is the most abundant type of phytosterol or plant sterol and can be found in
various plant dietary sources including natural oils, soy products, and nuts. Numerous …

Phytosterol-loaded surface-tailored bioactive-polymer nanoparticles for cancer treatment: Optimization, in vitro cell Viability, antioxidant activity, and stability studies

S Karim, MH Akhter, AS Burzangi, H Alkreathy… - Gels, 2022 - mdpi.com
This study aimsto optimize, characterize, and assess the phytosterol-loaded surface-tailored
bioactive Alginate/Chitosan NPs for antitumor efficacy against breast cancer. β-Sitosterol …

Harnessing folate-functionalized nasal delivery of dox–erlo-loaded biopolymeric nanoparticles in cancer treatment: development, optimization, characterization, and …

M Farheen, MH Akhter, H Chitme, MS Akhter… - Pharmaceuticals, 2023 - mdpi.com
The aim of the present study is to develop Doxorubicin–Erlotinib nanoparticles (Dox–Erlo
NPs) and folate-armored Dox–Erlo-NP conjugates for targeting glioma cancer. Glioma is …

Development, characterization, and evaluation of α-Mangostin-loaded polymeric nanoparticle gel for topical therapy in skin Cancer

S Md, NA Alhakamy, T Neamatallah, S Alshehri… - Gels, 2021 - mdpi.com
The aim of this study was to prepare and evaluate α-mangostin-loaded polymeric
nanoparticle gel (α-MNG-PLGA) formulation to enhance α-mangostin delivery in an …

[HTML][HTML] Beyond the adverse effects of the systemic route: exploiting nanocarriers for the topical treatment of skin cancers

B da Silva Gomes, AC Paiva-Santos, F Veiga… - Advanced Drug Delivery …, 2024 - Elsevier
Skin cancer is a heterogeneous disease that can be divided into two main groups,
melanoma and nonmelanoma skin cancers. Conventional therapies for skin cancer have …

Topical administration of drugs incorporated in carriers containing phospholipid soft vesicles for the treatment of skin medical conditions

E Touitou, H Natsheh - Pharmaceutics, 2021 - mdpi.com
This review focuses on the improved topical treatment of various medical skin conditions by
the use of drugs delivered from carriers containing phospholipid soft vesicles. Topical drug …