Recent technological advances have opened unprecedented opportunities for large-scale
sequencing and analysis of populations of pathogenic species in disease outbreaks, as well …

Metabolism underpins the physiology and pathogenesis of Mycobacterium tuberculosis.
However, although experimental mycobacteriology has provided key insights into the …

The treatment of tuberculosis is extremely long. One of the reasons why Mycobacterium
tuberculosis elimination from the organism takes so long is that in particular environmental …

The source of the microbial genomic sequences in the RefSeq collection is the set of primary
sequence records submitted to the International Nucleotide Sequence Database public …

Genome annotation is, nowadays, performed via automatic pipelines that cannot
discriminate between right and wrong annotations. Given their importance in increasing the …

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second major cause of
death from an infectious disease worldwide. Recent advances in DNA sequencing are …

Every day approximately six thousand people die of Tuberculosis (TB). Its causative agent,
Mycobacterium tuberculosis (Mtb), is an ancient pathogen that through its evolution …

Escherichia coli AraC is a well-described transcription activator of genes involved in
arabinose metabolism. Using complementary genomic approaches, chromatin …

We report here an update to the reference genome sequence of the bovine tuberculosis
bacillus Mycobacterium bovis AF2122/97, generated using an integrative multiomics …

Bacterial pathogens adapt to changing environments within their hosts, and the signaling
molecule adenosine 3′, 5′-cyclic monophosphate (cAMP) facilitates this process. In this …