[HTML][HTML] Lipid peroxidation and antioxidant protection

L Valgimigli - Biomolecules, 2023 - mdpi.com
Lipid peroxidation (LP) is the most important type of oxidative-radical damage in biological
systems, owing to its interplay with ferroptosis and to its role in secondary damage to other …

Revisiting carotenoids as dietary antioxidants for human health and disease prevention

J Terao - Food & Function, 2023 - pubs.rsc.org
Humans are unique indiscriminate carotenoid accumulators, so the human body
accumulates a wide range of dietary carotenoids of different types and to varying …

Singlet molecular oxygen reactions with nucleic acids, lipids, and proteins

P Di Mascio, GR Martinez, S Miyamoto… - Chemical …, 2019 - ACS Publications
Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Activatable singlet oxygen generation from lipid hydroperoxide nanoparticles for cancer therapy

Z Zhou, J Song, R Tian, Z Yang, G Yu, L Lin… - Angewandte …, 2017 - Wiley Online Library
Reactive oxygen species (ROS)‐induced apoptosis is a widely practiced strategy for cancer
therapy. Although photodynamic therapy (PDT) takes advantage of the spatial–temporal …

Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence

E Niki - Free Radical Biology and Medicine, 2014 - Elsevier
Multiple reactive oxygen/nitrogen species induce oxidative stress. Mammals have evolved
with an elaborate defense network against oxidative stress, in which multiple antioxidant …

Significance of singlet oxygen molecule in pathologies

K Murotomi, A Umeno, M Shichiri, M Tanito… - International Journal of …, 2023 - mdpi.com
Reactive oxygen species, including singlet oxygen, play an important role in the onset and
progression of disease, as well as in aging. Singlet oxygen can be formed non …

Lipid peroxidation: physiological levels and dual biological effects

E Niki - Free radical biology and medicine, 2009 - Elsevier
Lipid peroxidation (LPO) has been shown to induce disturbance of membrane organization
and functional loss and modification of proteins and DNA bases, and it has been implicated …

Generation and biological activities of oxidized phospholipids

VN Bochkov, OV Oskolkova, KG Birukov… - Antioxidants & redox …, 2010 - liebertpub.com
Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …