The evolution of insect metamorphosis is one of the most important sagas in animal history,
transforming small, obscure soil arthropods into a dominant terrestrial group that has …

This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Cancer cachexia syndrome is a major cause of morbidity and mortality in cancer patients in
the advanced stage. It is a devastating disorder characterized by nutritional impairment …

Energy metabolism is a basic and general process, by which the body acquires and uses
energy to maintain normal function, and taurine plays a vital role in energy metabolism …

Brain-derived extracellular vesicles participate in interorgan communication after traumatic
brain injury by transporting pathogens to initiate secondary injury. Inflammasome-related …

Carbohydrate metabolism is essential for cellular energy balance as well as for the
biosynthesis of new cellular building blocks. As animal nutrient intake displays temporal …

Mounting an immune response is an energy-consuming process. Activating immune
functions requires the synthesis of many new molecules and the undertaking of numerous …

Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

Neurodegeneration in the central nervous system (CNS) is a defining feature of organismal
aging that is influenced by peripheral tissues. Clinical observations indicate that skeletal …