Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?
CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …
Mitochondria as cellular and organismal signaling hubs
Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …
extend far beyond energy production. They are vital in cellular and organismal pathways …
Mitochondrial calcium exchange in physiology and disease
JF Garbincius, JW Elrod - Physiological reviews, 2022 - journals.physiology.org
The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …
fundamental biological process that has critical effects on cellular metabolism, signaling …
The integration of reactive oxygen species (ROS) and calcium signalling in abiotic stress responses
Reactive oxygen species (ROS) and calcium (Ca2+) signalling are interconnected in the
perception and transmission of environmental signals that control plant growth, development …
perception and transmission of environmental signals that control plant growth, development …
The machineries, regulation and cellular functions of mitochondrial calcium
Abstract Calcium ions (Ca2+) are some of the most versatile signalling molecules, and they
have many physiological functions, prominently including muscle contraction, neuronal …
have many physiological functions, prominently including muscle contraction, neuronal …
Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
PR Angelova, AY Abramov - FEBS letters, 2018 - Wiley Online Library
Mitochondria are key cell organelles in that they are responsible for energy production and
control many processes from signalling to cell death. The function of the mitochondrial …
control many processes from signalling to cell death. The function of the mitochondrial …
[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …
molecules coordinating physiological and pathophysiological processes. While channels …
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease
Impairments in neuronal intracellular calcium (iCa2+) handling may contribute to
Alzheimer's disease (AD) development. Metabolic dysfunction and progressive neuronal …
Alzheimer's disease (AD) development. Metabolic dysfunction and progressive neuronal …
Role of cardiolipin in mitochondrial signaling pathways
J Dudek - Frontiers in cell and developmental biology, 2017 - frontiersin.org
The phospholipid cardiolipin (CL) is an essential constituent of mitochondrial membranes
and plays a role in many mitochondrial processes, including respiration and energy …
and plays a role in many mitochondrial processes, including respiration and energy …
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages
Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …