Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?

CL Kuo, A Ponneri Babuharisankar, YC Lin… - Journal of biomedical …, 2022 - Springer
The major concept of" oxidative stress" is an excess elevated level of reactive oxygen
species (ROS) which are generated from vigorous metabolism and consumption of oxygen …

Mitochondria as cellular and organismal signaling hubs

K Shen, CL Pender, R Bar-Ziv, H Zhang… - Annual review of cell …, 2022 - annualreviews.org
Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …

Mitochondrial calcium exchange in physiology and disease

JF Garbincius, JW Elrod - Physiological reviews, 2022 - journals.physiology.org
The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

The integration of reactive oxygen species (ROS) and calcium signalling in abiotic stress responses

B Ravi, CH Foyer, GK Pandey - Plant, Cell & Environment, 2023 - Wiley Online Library
Reactive oxygen species (ROS) and calcium (Ca2+) signalling are interconnected in the
perception and transmission of environmental signals that control plant growth, development …

The machineries, regulation and cellular functions of mitochondrial calcium

C Giorgi, S Marchi, P Pinton - Nature reviews Molecular cell biology, 2018 - nature.com
Abstract Calcium ions (Ca2+) are some of the most versatile signalling molecules, and they
have many physiological functions, prominently including muscle contraction, neuronal …

Role of mitochondrial ROS in the brain: from physiology to neurodegeneration

PR Angelova, AY Abramov - FEBS letters, 2018 - Wiley Online Library
Mitochondria are key cell organelles in that they are responsible for energy production and
control many processes from signalling to cell death. The function of the mitochondrial …

[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases

CT Madreiter-Sokolowski, C Thomas, M Ristow - Redox biology, 2020 - Elsevier
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease

P Jadiya, DW Kolmetzky, D Tomar, A Di Meco… - Nature …, 2019 - nature.com
Impairments in neuronal intracellular calcium (iCa2+) handling may contribute to
Alzheimer's disease (AD) development. Metabolic dysfunction and progressive neuronal …

Role of cardiolipin in mitochondrial signaling pathways

J Dudek - Frontiers in cell and developmental biology, 2017 - frontiersin.org
The phospholipid cardiolipin (CL) is an essential constituent of mitochondrial membranes
and plays a role in many mitochondrial processes, including respiration and energy …

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …