Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
Construction of sulfur-containing moieties in the total synthesis of natural products
N Wang, P Saidhareddy, X Jiang - Natural Product Reports, 2020 - pubs.rsc.org
Covering: January 2013 to September 2018 Sulfur-containing natural products are a large
class of significant functional molecules. Many of these compounds exhibit potent biological …
class of significant functional molecules. Many of these compounds exhibit potent biological …
A survey of the role of noncovalent sulfur interactions in drug design
BR Beno, KS Yeung, MD Bartberger… - Journal of medicinal …, 2015 - ACS Publications
Electron deficient, bivalent sulfur atoms have two areas of positive electrostatic potential, a
consequence of the low-lying σ* orbitals of the C–S bond that are available for interaction …
consequence of the low-lying σ* orbitals of the C–S bond that are available for interaction …
Marine natural products
Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …
[HTML][HTML] Natural products as reservoirs of novel therapeutic agents
Since ancient times, natural products from plants, animals, microbial and marine sources
have been exploited for treatment of several diseases. The knowledge of our ancestors is …
have been exploited for treatment of several diseases. The knowledge of our ancestors is …
Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A
K Yamanaka, KA Reynolds… - Proceedings of the …, 2014 - National Acad Sciences
Recent developments in next-generation sequencing technologies have brought recognition
of microbial genomes as a rich resource for novel natural product discovery. However …
of microbial genomes as a rich resource for novel natural product discovery. However …
[HTML][HTML] Marine actinomycetes: an ongoing source of novel bioactive metabolites
R Subramani, W Aalbersberg - Microbiological research, 2012 - Elsevier
Actinomycetes are virtually unlimited sources of novel compounds with many therapeutic
applications and hold a prominent position due to their diversity and proven ability to …
applications and hold a prominent position due to their diversity and proven ability to …
Microbial natural products in drug discovery
Over a long period of time, humans have explored many natural resources looking for
remedies of various ailments. Traditional medicines have played an intrinsic role in human …
remedies of various ailments. Traditional medicines have played an intrinsic role in human …
Marine natural products
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …
literature published in 2009 for marine natural products, with 857 citations (588 for the …
Immense essence of excellence: marine microbial bioactive compounds
I Bhatnagar, SK Kim - Marine drugs, 2010 - mdpi.com
Oceans have borne most of the biological activities on our planet. A number of biologically
active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti …
active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti …