Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

The latest advances in high-throughput techniques during the past decade allowed the
systems biology field to expand significantly. Today, the focus of biologists has shifted from …

Biological networks capture structural or functional properties of relevant entities such as
molecules, proteins or genes. Characteristic examples are gene expression networks or …

Bioinformatics pipelines are essential in the analysis of genomic and transcriptomic data
generated by next-generation sequencing (NGS). Recent guidelines emphasize the need …

Stress granules (SGs) are dynamic, membrane-less organelles. With their formation and
disassembly processes characterized, it remains elusive how compositional transitions are …

Background The gut microbiota impacts on a range of host biological processes, and the
imbalances in its composition are associated with pathology. Though the understanding of …

The immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of
this bioinformatics-assisted review was twofold;(i) to update the current knowledge of Fe …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy, accounting
for over 90% of pancreatic cancers, and is characterized by limited treatment options and …

This systematic review aims to provide a comprehensive overview of graph-based
methodologies utilized in the analysis of protein–protein interaction (PPI) networks. The …

Finding, exploring and filtering frequent sentence-based associations between a disease
and a biomedical entity, co-mentioned in disease-related PubMed literature, is a challenge …