High-quality point-of-care is critical for timely decision of disease diagnosis and healthcare
management. In this regard, biosensors have revolutionized the field of rapid testing and …

Imaging plays a pivotal role in the precise diagnosis of a variety of diseases. Various
imaging modalities have long secured their place in clinics. However, a lot of these …

Genetic studies have identified≥ 240 loci associated with the risk of type 2 diabetes (T2D),
yet most of these loci lie in non-coding regions, masking the underlying molecular …

Monitoring blood glucose levels for diabetic patients is critical to achieve tight glycaemic
control. As none of the current antidiabetic treatments restore lost functional β-cell mass in …

Stem cell-derived islet organoids constitute a promising treatment of type 1 diabetes. A
major hurdle in the field is the lack of appropriate in vivo method to determine graft outcome …

Human islet transplantations into rodent models are an essential tool to aid in the
development and testing of islet and cellular-based therapies for diabetes prevention and …

Type 1 diabetes mellitus (T1DM) has been defined as an autoimmune disease
characterised by immune-mediated destruction of the pancreatic β cells, leading to absolute …

Pancreatic islet cells, and in particular insulin-producing beta cells, are centrally involved in
the pathogenesis of diabetes mellitus. These cells are of paramount importance for the …

Autoimmune diseases (AIDs) generally manifest as chronic immune disorders characterized
by significant heterogeneity and complex symptoms. The discordant incidence of AIDs …

Purpose Current approaches to quantification of magnetic particle imaging (MPI) for cell-
based therapy are thwarted by the lack of reliable, standardized methods of segmenting the …