Overcoming barriers to patient adherence: the case for develo** innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Exploiting unique features of microneedles to modulate immunity

C Edwards, SA Shah, T Gebhardt… - Advanced …, 2023 - Wiley Online Library
Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …

Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis: Report of the Guideline Development, Dissemination …

A Rae-Grant, GS Day, RA Marrie, A Rabinstein… - Neurology, 2018 - neurology.org
Objective To develop recommendations for disease-modifying therapy (DMT) for multiple
sclerosis (MS). Methods A multidisciplinary panel developed DMT recommendations …

The Global Adherence Project (GAP): A multicenter observational study on adherence to disease‐modifying therapies in patients with relapsing‐remitting multiple …

V Devonshire, Y Lapierre, R Macdonell… - European Journal of …, 2011 - Wiley Online Library
Background: Most disease‐modifying therapies (DMTs) for multiple sclerosis (MS) are self‐
injectable medications that must be taken on an ongoing basis to reduce disease activity …

Factors affecting adherence to disease-modifying therapies in multiple sclerosis: systematic review

F Washington, D Langdon - Journal of neurology, 2022 - Springer
People with multiple sclerosis (MS) face challenges adhering to disease-modifying drug
(DMD) treatment. Poor adherence to treatment reduces its clinical effectiveness which can …

Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

Narrative review of the literature on adherence to disease-modifying therapies among patients with multiple sclerosis

J Menzin, C Caon, C Nichols, LA White… - Journal of managed …, 2013 - jmcp.org
While no curative treatment exists for multiple sclerosis (MS), several disease-modifying
therapies (DMTs) have been developed to reduce relapse rates, slow disability progression …

Impact of adherence to disease-modifying therapies on clinical and economic outcomes among patients with multiple sclerosis

H Tan, Q Cai, S Agarwal, JJ Stephenson, S Kamat - Advances in therapy, 2011 - Springer
Background Adherence to disease-modifying therapies (DMTs) is essential for the reduction
of multiple sclerosis (MS) progression and relapse. However, only limited data currently exist …

Impact of adherence to interferons in the treatment of multiple sclerosis: a non-experimental, retrospective, cohort study

SC Steinberg, RJ Faris, CF Chang, A Chan… - Clinical drug …, 2010 - Springer
Background: Relapsing-remitting multiple sclerosis (RRMS) is a chronic disease affecting
about 400 000 people in the US characterized by increasing patient disability and burden on …

[HTML][HTML] Achieving patient engagement in multiple sclerosis: a perspective from the multiple sclerosis in the 21st Century Steering Group

P Rieckmann, A Boyko, D Centonze, I Elovaara… - Multiple Sclerosis and …, 2015 - Elsevier
While advances in medicine, technology and healthcare services offer promises of longevity
and improved quality of life (QoL), there is also increasing reliance on a patient׳ s skills and …