Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

The mycelia polysaccharides (MPS) from Pleurotus djamor were prepared and purified by
anion exchange column chromatography, and the phosphate content of phosphorylated …

Cisplatin remains the standard first-line chemotherapeutic agent in the treatment of many
types of cancers, but its clinical application is hindered by its severe nephrotoxicity. Previous …

Contrast-Induced Acute Kidney Injury (CI-AKI) remains a frequent iatrogenic condition since
radiological procedures using intra-vascular iodinated contrast media (CM) are being widely …

Introduction Cisplatin, an anti-cancer drug is used to treat a wide range of solid tumors.
Nevertheless, nephrotoxicity is the major adverse effect that restricts its clinical application …

Cisplatin (CP) is a productive anti-tumor used to treat numerous tumors. However, multiple
toxicities discourage prolonged use, especially toxicity on the reproductive system. This …

Cisplatin (CP) is a well-known anticancer drug used to effectively treat various kinds of solid
tumors. CP causes acute kidney injury (AKI) and unfortunately, there is no therapeutic …

Glaucoma is a neurodegenerative disease that causes blindness. In this study, we aimed to
evaluate the protective role of cilastatin (CIL), generally used in the treatment of …

Gentamicin is a used antibiotic that causes nephrotoxicity in 10–20% of treatment periods,
which limits its use considerably. Our results have shown that cilastatin may be a promising …