Campylobacter sp.: Pathogenicity factors and prevention methods—new molecular targets for innovative antivirulence drugs?

V Kreling, FH Falcone, C Kehrenberg… - Applied Microbiology and …, 2020 - Springer
Infections caused by bacterial species from the genus Campylobacter are one of the four
main causes of strong diarrheal enteritis worldwide. Campylobacteriosis, a typical food …

Synthetic biology-inspired cell engineering in diagnosis, treatment, and drug development

N Zhao, Y Song, X ** synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …

Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin

Z He, RZ Gharaibeh, RC Newsome, JL Pope… - Gut, 2019 - gut.bmj.com
Objective Campylobacter jejuni produces a genotoxin, cytolethal distending toxin (CDT),
which has DNAse activity and causes DNA double-strand breaks. Although C. jejuni …

Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and …

M Bielaszewska, C Rüter, A Bauwens, L Greune… - PLoS …, 2017 - journals.plos.org
Outer membrane vesicles (OMVs) are important tools in bacterial virulence but their role in
the pathogenesis of infections caused by enterohemorrhagic Escherichia coli (EHEC) O157 …

The roles of microbial products in the development of colorectal cancer: a review

Y Fang, C Yan, Q Zhao, J Xu, Z Liu, J Gao, H Zhu… - …, 2021 - Taylor & Francis
ABSTRACT A large number of microbes exist in the gut and they have the ability to process
and utilize ingested food. It has been reported that their products are involved in colorectal …

Periodontal pathogens and their links to neuroinflammation and neurodegeneration

D Visentin, I Gobin, Ž Maglica - Microorganisms, 2023 - mdpi.com
Pathogens that play a role in the development and progression of periodontitis have gained
significant attention due to their implications in the onset of various systemic diseases …

Campylobacter Virulence Factors and Molecular Host–Pathogen Interactions

N Tegtmeyer, I Sharafutdinov, A Harrer… - … Infections: Towards a …, 2021 - Springer
Campylobacter jejuni and Campylobacter coli can be frequently isolated from poultry and
poultry-derived products, and in combination these two species cause a large portion of …

[HTML][HTML] Virulence factors of foodborne pathogen Campylobacter jejuni

GV Lopes, T Ramires, NR Kleinubing, LK Scheik… - Microbial …, 2021 - Elsevier
Campylobacter jejuni is a highly frequent cause of gastrointestinal foodborne disease in
humans throughout the world. Disease outcomes vary from mild to severe diarrhea, and in …

Genotoxins: The Mechanistic Links between Escherichia coli and Colorectal Cancer

Y Wang, K Fu - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a leading cause of cancer-related mortality
worldwide, and its incidence is steadily rising in develo** areas. Bacterial pathogens from …

Bacterial genotoxins: merging the DNA damage response into infection biology

F Grasso, T Frisan - Biomolecules, 2015 - mdpi.com
Bacterial genotoxins are unique among bacterial toxins as their molecular target is DNA.
The consequence of intoxication or infection is induction of DNA breaks that, if not properly …