The development of methods that enabled genome-wide map** of DNA G-quadruplex
structures in chromatin has played a critical role in providing evidence to support the …

Conspectus The ability of genomic DNA to adopt non-canonical secondary structures known
as G-quadruplexes (G4s) under physiological conditions has been recognized for its …

In nucleotide expansion disorders, RNA foci are reportedly associated with
neurodegenerative disease pathogeneses. Characteristically, these RNAs exhibit long poly …

Although the role of G-quadruplex (G4) DNA structures has been suggested in chromosomal
loo** this was not tested directly. Here, to test causal function, an array of G4s, or control …

An i‐motif is a non‐canonical DNA structure implicated in gene regulation and linked to
cancers. The C‐rich strand of the HRAS oncogene, 5′‐CG CCC GTG CCC TGCG CCC …

G-quadruplexes (G4s) have long been implicated in the regulation of chromatin packaging
and gene expression. These processes require or are accelerated by the separation of …

Bimolecular or tetramolecular G-quadruplexes (GQs) are predominantly self-assembled by
the same sequence-identical G-rich oligonucleotides and usually remain inert to the strand …

Guanine quadruplexes (G4s) play essential protective and regulatory roles within cells,
influencing gene expression. In several gene-promoter regions, multiple G4-forming …

Simple Summary Genomic instability is an important feature of cancer, including multiple
myeloma, which is the second most common hematological malignancy. There are several …

Genome-wide studies have demonstrated regulatory roles for diverse non-coding elements,
but their precise and interrelated functions have often remained enigmatic. Addressing the …