Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets

E Ioannidou, M Moschetta, S Shah, JS Parker… - International journal of …, 2021 - mdpi.com
Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …

The role of the VEGF-C/VEGFR-3 axis in cancer progression

JL Su, CJ Yen, PS Chen, SE Chuang, CC Hong… - British journal of …, 2007 - nature.com
Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR-3)(also called VEGFR-3) is
activated by its specific ligand, VEGF-C, which promotes cancer progression. The VEGF …

Stromal vascular fraction improves deep partial thickness burn wound healing

S Atalay, A Coruh, K Deniz - Burns, 2014 - Elsevier
Objective The practice of early burn wound excision and wound closure by immediate
autologous skin or skin substitutes is the preferred treatment in extensive deep partial and …

Molecular markers of prostate cancer outcome

DI Quinn, SM Henshall, RL Sutherland - European journal of cancer, 2005 - Elsevier
Molecular markers have the potential to serve not only as prognostic factors but may be
targets for new therapeutic strategies and predictors of response in a range of cancers …

Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node …

SY Wong, H Haack, D Crowley, M Barry, RT Bronson… - Cancer research, 2005 - AACR
Dissemination to draining lymph nodes is a frequent first step in prostate cancer metastasis.
Although tumors metastasize to lymph nodes via the lymphatics, the importance of …

Hypoxia and prostate cancer aggressiveness: a tale with many endings

A Fraga, R Ribeiro, P Príncipe, C Lopes… - Clinical genitourinary …, 2015 - Elsevier
Angiogenesis, increased glycolysis, and cellular adaptation to hypoxic microenvironment
are characteristic of solid tumors, including prostate cancer. These representative features …

Mechanism of lymph node metastasis in prostate cancer

K Datta, M Muders, H Zhang, DJ Tindall - Future oncology, 2010 - Taylor & Francis
Detection of lymph node metastases indicates poor prognosis for prostate cancer patients.
Therefore, elucidation of the mechanism (s) of lymph node metastasis is important to …

The role of the VEGF-C/VEGFRs axis in tumor progression and therapy

JC Chen, YW Chang, CC Hong, YH Yu… - International journal of …, 2012 - mdpi.com
Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …

Expression of vascular endothelial growth factor C (VEGF‐C) and VEGF receptor‐3 in human prostate cancer is associated with regional lymph node metastasis

K Jennbacken, C Vallbo, W Wang, JE Damber - The Prostate, 2005 - Wiley Online Library
BACKGROUND Vascular endothelial growth factor C (VEGF‐C) and its receptor, VEGFR‐3,
have been implicated as important factors in the formation of lymphatic vessels and recent …

Biomarkers for evaluation of prostate cancer prognosis

M Esfahani, N Ataei, M Panjehpour - Asian Pacific Journal of …, 2015 - koreascience.kr
Prostate cancer, with a lifetime prevalence of one in six men, is the second cause of
malignancy-related death and the most prevalent cancer in men in many countries …