Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets
Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …
cancer-related death worldwide. Many therapeutic advances over the last two decades have …
The role of the VEGF-C/VEGFR-3 axis in cancer progression
JL Su, CJ Yen, PS Chen, SE Chuang, CC Hong… - British journal of …, 2007 - nature.com
Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR-3)(also called VEGFR-3) is
activated by its specific ligand, VEGF-C, which promotes cancer progression. The VEGF …
activated by its specific ligand, VEGF-C, which promotes cancer progression. The VEGF …
Stromal vascular fraction improves deep partial thickness burn wound healing
Objective The practice of early burn wound excision and wound closure by immediate
autologous skin or skin substitutes is the preferred treatment in extensive deep partial and …
autologous skin or skin substitutes is the preferred treatment in extensive deep partial and …
Molecular markers of prostate cancer outcome
DI Quinn, SM Henshall, RL Sutherland - European journal of cancer, 2005 - Elsevier
Molecular markers have the potential to serve not only as prognostic factors but may be
targets for new therapeutic strategies and predictors of response in a range of cancers …
targets for new therapeutic strategies and predictors of response in a range of cancers …
Tumor-secreted vascular endothelial growth factor-C is necessary for prostate cancer lymphangiogenesis, but lymphangiogenesis is unnecessary for lymph node …
SY Wong, H Haack, D Crowley, M Barry, RT Bronson… - Cancer research, 2005 - AACR
Dissemination to draining lymph nodes is a frequent first step in prostate cancer metastasis.
Although tumors metastasize to lymph nodes via the lymphatics, the importance of …
Although tumors metastasize to lymph nodes via the lymphatics, the importance of …
Hypoxia and prostate cancer aggressiveness: a tale with many endings
A Fraga, R Ribeiro, P Príncipe, C Lopes… - Clinical genitourinary …, 2015 - Elsevier
Angiogenesis, increased glycolysis, and cellular adaptation to hypoxic microenvironment
are characteristic of solid tumors, including prostate cancer. These representative features …
are characteristic of solid tumors, including prostate cancer. These representative features …
Mechanism of lymph node metastasis in prostate cancer
K Datta, M Muders, H Zhang, DJ Tindall - Future oncology, 2010 - Taylor & Francis
Detection of lymph node metastases indicates poor prognosis for prostate cancer patients.
Therefore, elucidation of the mechanism (s) of lymph node metastasis is important to …
Therefore, elucidation of the mechanism (s) of lymph node metastasis is important to …
The role of the VEGF-C/VEGFRs axis in tumor progression and therapy
JC Chen, YW Chang, CC Hong, YH Yu… - International journal of …, 2012 - mdpi.com
Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …
Expression of vascular endothelial growth factor C (VEGF‐C) and VEGF receptor‐3 in human prostate cancer is associated with regional lymph node metastasis
K Jennbacken, C Vallbo, W Wang, JE Damber - The Prostate, 2005 - Wiley Online Library
BACKGROUND Vascular endothelial growth factor C (VEGF‐C) and its receptor, VEGFR‐3,
have been implicated as important factors in the formation of lymphatic vessels and recent …
have been implicated as important factors in the formation of lymphatic vessels and recent …
Biomarkers for evaluation of prostate cancer prognosis
M Esfahani, N Ataei, M Panjehpour - Asian Pacific Journal of …, 2015 - koreascience.kr
Prostate cancer, with a lifetime prevalence of one in six men, is the second cause of
malignancy-related death and the most prevalent cancer in men in many countries …
malignancy-related death and the most prevalent cancer in men in many countries …