Molecular spatiomics by proximity labeling
Conspectus Proximity labeling can be defined as an enzymatic “in-cell” chemical reaction
that catalyzes the proximity-dependent modification of biomolecules in live cells. Since the …
that catalyzes the proximity-dependent modification of biomolecules in live cells. Since the …
Supramolecular chemistry of substituted cucurbit [n] urils
RL Lin, JX Liu, K Chen, C Redshaw - Inorganic Chemistry Frontiers, 2020 - pubs.rsc.org
Since the first example of substituted cucurbit [n] urils (Q [n]), decamethylcucurbit [5] uril
(Me10Q [5]), was reported in 1992, numerous substituted Q [n] s have been synthesized and …
(Me10Q [5]), was reported in 1992, numerous substituted Q [n] s have been synthesized and …
Synthetic host-guest pairs as novel bioorthogonal tools for pre-targeting
YL Ma, S Yan, XJ Xu, H Cao, R Wang - Chinese Chemical Letters, 2024 - Elsevier
Due to its simplicity, high efficiency, and chemo-selectivity, bioorthogonal chemistry has
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
Biomimetic recognition-based bioorthogonal host–guest pairs for cell targeting and tissue imaging in living animals
Bioconjugation methods offer very important tools in studying biological systems. Synthetic
host–guest pairs provide an alternative and complementary conjugation method to …
host–guest pairs provide an alternative and complementary conjugation method to …
Purification of protein therapeutics via high-affinity supramolecular host–guest interactions
Efficient purification is crucial to providing large quantities of recombinant therapeutic
proteins, such as monoclonal antibodies and cytokines. However, affinity techniques for …
proteins, such as monoclonal antibodies and cytokines. However, affinity techniques for …
OrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools
Identifying proteins at organelle contact sites, such as mitochondria-associated endoplasmic
reticulum membranes (MAM), is essential for understanding vital cellular processes, yet …
reticulum membranes (MAM), is essential for understanding vital cellular processes, yet …
A Combination of Bio‐Orthogonal Supramolecular Clicking and Proximity Chemical Tagging as a Supramolecular Tool for Discovery of Putative Proteins Associated …
Protein mutations alter protein–protein interactions that can lead to a number of illnesses.
Mutations in lamin A (LMNA) have been reported to cause laminopathies. However, the …
Mutations in lamin A (LMNA) have been reported to cause laminopathies. However, the …
Cucurbiturils Monofunctionalized on the Methylene Bridge and Their Host‐Guest Properties
M Kandrnálová, V Šindelář - European Journal of Organic …, 2021 - Wiley Online Library
Monofunctionalization of cucurbiturils is essential for transferring these potent
supramolecular macrocyclic hosts into real‐world application. Here, we present the …
supramolecular macrocyclic hosts into real‐world application. Here, we present the …
Identification of mitochondrial proteins associated with cyanine 5 using a combination of affinity-based photocrosslinking with bio-orthogonal supramolecular latching
J Sim, M Li, KM Park, K Kim - Journal of Porphyrins and …, 2023 - World Scientific
Visualization of mitochondria with cyanine dyes has been exploited to study the functions of
mitochondria. However, proteins interacting with cyanine dyes have not been investigated …
mitochondria. However, proteins interacting with cyanine dyes have not been investigated …