Despite decades of laboratory, epidemiological and clinical research, breast cancer
incidence continues to rise. Breast cancer remains the leading cancer-related cause of …

Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

We performed a scan for genetic variants associated with multiple phenotypes by comparing
large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

Males and females share many traits that have a common genetic basis; however, selection
on these traits often differs between the sexes, leading to sexual conflict,. Under such sexual …

The onset of puberty in adolescents and whether it is related to obesity is an ongoing topic
for debate. Epidemiological cross-sectional and longitudinal studies show a shift towards …

Genetic predisposition to obesity presents a paradox: how do genetic variants with a
detrimental impact on human health persist through evolutionary time? Numerous …

Single nucleotide polymorphisms (SNPs) that cluster in the first intron of fat mass and
obesity associated (FTO) gene are associated obesity traits in genome-wide association …

Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes …

Human genetics has been haunted by the mystery of “missing heritability” of common traits.
Although studies have discovered> 1,200 variants associated with common diseases and …