Eighteen nucleic acid therapeutics have been approved for treatment of various diseases in
the last 25 years. Their modes of action include antisense oligonucleotides (ASOs), splice …

Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

The weighted ensemble (WE) strategy has been demonstrated to be highly efficient in
generating pathways and rate constants for rare events such as protein folding and protein …

Many biomineral crystals form complex non-equilibrium shapes, often via transient
amorphous precursors. Also in vitro crystals can be grown with non-equilibrium …

Over two decades have passed since the fifth edition of Phosphorus: Chemistry,
Biochemistry and Technology. Major advances in chemistry, materials science, electronics …

Revised Manuscript Received August 14, 1989 abstract: The anticancer drugs adriamycin
and daunomycin have each been crystallized with the DNA sequence d (CGATCG) and the …

Genomic DNA base composition (GC content) is predicted to significantly affect genome
functioning and species ecology. Although several hypotheses have been put forward to …

The crystal structure of the monoclinic form of yeast phenylalanine tRNA has been
redetermined at a resolution of 1.93 Å. The structure of yeast tRNAphe described here is …

A suite of mechanisms or processes that together have been implicated in the acquisition
and maintenance of desiccation tolerance in orthodox seeds is discussed in the context of …

Repeat tracts of guanine bases found in DNA and RNA can form tetraplex structures in the
presence of a variety of monovalent cations. Evidence suggests that guanine tetraplexes …