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Reconstructing computational system dynamics from neural data with recurrent neural networks
Computational models in neuroscience usually take the form of systems of differential
equations. The behaviour of such systems is the subject of dynamical systems theory …
equations. The behaviour of such systems is the subject of dynamical systems theory …
[HTML][HTML] The quest for multiscale brain modeling
Addressing the multiscale organization of the brain, which is fundamental to the dynamic
repertoire of the organ, remains challenging. In principle, it should be possible to model …
repertoire of the organ, remains challenging. In principle, it should be possible to model …
Spontaneous behaviors drive multidimensional, brainwide activity
INTRODUCTION In the absence of sensory inputs, the brain produces structured patterns of
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …
Integrated information theory: from consciousness to its physical substrate
In this Opinion article, we discuss how integrated information theory accounts for several
aspects of the relationship between consciousness and the brain. Integrated information …
aspects of the relationship between consciousness and the brain. Integrated information …
The role of variability in motor learning
Trial-to-trial variability in the execution of movements and motor skills is ubiquitous and
widely considered to be the unwanted consequence of a noisy nervous system. However …
widely considered to be the unwanted consequence of a noisy nervous system. However …
Robust neuronal dynamics in premotor cortex during motor planning
Neural activity maintains representations that bridge past and future events, often over many
seconds. Network models can produce persistent and ram** activity, but the positive …
seconds. Network models can produce persistent and ram** activity, but the positive …
Efficient codes and balanced networks
Recent years have seen a growing interest in inhibitory interneurons and their circuits. A
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
striking property of cortical inhibition is how tightly it balances excitation. Inhibitory currents …
Consciousness is supported by near-critical slow cortical electrodynamics
Mounting evidence suggests that during conscious states, the electrodynamics of the cortex
are poised near a critical point or phase transition and that this near-critical behavior …
are poised near a critical point or phase transition and that this near-critical behavior …
Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo
We describe an all-optical strategy for simultaneously manipulating and recording the
activity of multiple neurons with cellular resolution in vivo. We performed simultaneous two …
activity of multiple neurons with cellular resolution in vivo. We performed simultaneous two …
Single-neuron perturbations reveal feature-specific competition in V1
The computations performed by local neural populations, such as a cortical layer, are
typically inferred from anatomical connectivity and observations of neural activity. Here we …
typically inferred from anatomical connectivity and observations of neural activity. Here we …