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G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs
Although cisplatin and its analogues have been widely utilized as anticancer metallodrugs
in clinics, their serious side effects and damage to normal tissues cannot be avoided …
in clinics, their serious side effects and damage to normal tissues cannot be avoided …
Applications of ruthenium complex in tumor diagnosis and therapy
K Lin, ZZ Zhao, HB Bo, XJ Hao, JQ Wang - Frontiers in Pharmacology, 2018 - frontiersin.org
Ruthenium complexes are a new generation of metal antitumor drugs that are currently of
great interest in multidisciplinary research. In this review article, we introduce the …
great interest in multidisciplinary research. In this review article, we introduce the …
Interaction of metal complexes with G‐quadruplex DNA
Guanine‐rich sequences of DNA can assemble into tetrastranded structures known as G‐
quadruplexes. It has been suggested that these secondary DNA structures could be …
quadruplexes. It has been suggested that these secondary DNA structures could be …
Ruthenium coordination compounds of biological and biomedical significance. DNA binding agents
V Brabec, J Kasparkova - Coordination chemistry reviews, 2018 - Elsevier
Ruthenium complexes exhibit a broad variety of biological and biomedical activities
including anticancer efficiency. The reason is that the octahedral bonding of both Ru (II) and …
including anticancer efficiency. The reason is that the octahedral bonding of both Ru (II) and …
Platinum (II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA
DL Ma, CM Che, SC Yan - Journal of the American Chemical …, 2009 - ACS Publications
A series of platinum (II) complexes containing dipyridophenazine (dppz) and C-
deprotonated 2-phenylpyridine (N∧ CH) ligands were prepared and assayed for G …
deprotonated 2-phenylpyridine (N∧ CH) ligands were prepared and assayed for G …
Revolutionizing anticancer treatment: Ruthenium-based nanoplatforms pave new paths
Cancer ranks among the top causes of mortality on a global scale. The only treatments
available for cancer nowadays are surgery, radiation therapy, and the use of cytotoxic …
available for cancer nowadays are surgery, radiation therapy, and the use of cytotoxic …
Stabilization of G‐Quadruplex DNA with Platinum(II) Schiff Base Complexes: Luminescent Probe and Down‐Regulation of c‐myc Oncogene Expression
P Wu, DL Ma, CH Leung, SC Yan, N Zhu… - … A European Journal, 2009 - Wiley Online Library
The interactions of a series of platinum (II) Schiff base complexes with c‐myc G‐quadruplex
DNA were studied. Complex [PtL1a](1 a; H2L1a= N, N′‐bis (salicylidene)‐4, 5‐methoxy‐1 …
DNA were studied. Complex [PtL1a](1 a; H2L1a= N, N′‐bis (salicylidene)‐4, 5‐methoxy‐1 …
An overview of the potential medicinal and pharmaceutical properties of Ru (II)/(III) complexes
A Skoczynska, A Lewinski, M Pokora, P Paneth… - International Journal of …, 2023 - mdpi.com
This review examines the existing knowledge about Ru (II)/(III) ion complexes with a
potential application in medicine or pharmacy, which may offer greater potential in cancer …
potential application in medicine or pharmacy, which may offer greater potential in cancer …
Interactions of metal ions with DNA, its constituents and derivatives, which may be relevant for anticancer research
In this review several types of interactions between metal ions and DNA are given, starting
from basic binding to the use of metal complexes in cancer treatment and diagnostics. Metal …
from basic binding to the use of metal complexes in cancer treatment and diagnostics. Metal …
Interaction of [Ru (bpy) 2 (dppz)] 2+ with human telomeric DNA: Preferential binding to G-quadruplexes over i-motif
S Shi, X Geng, J Zhao, T Yao, C Wang, D Yang… - Biochimie, 2010 - Elsevier
Inspired by the enormous importance attributed to the structure and function of human
telomeric DNA, we focus our attention on the interaction of [Ru (bpy) 2 (dppz)] 2+ with the …
telomeric DNA, we focus our attention on the interaction of [Ru (bpy) 2 (dppz)] 2+ with the …