The liver is not only the main metabolic site of exogenous compounds and drugs, but also
an important immune organ in the human body. When a large number of nonself substances …

Impaired wound healing is one of the severe complications of diabetes. Macrophages have
been shown to play a vital role in wound healing. In different wound environments …

The Hedgehog pathway is essential for embryonic development but also for tissue and
organ homeostasis in adult organisms. Activation of this pathway leads to the expression of …

Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …

Abstract Background Cancer stem cells (CSCs) play an important role in the development of
pancreatic cancer. We previously showed that the microRNA miR-137 is downregulated in …

Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body's
immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted …

A significant clinical association between osteoporosis (OP) and fibromyalgia (FM) has been
shown in the literature. Given the need for specific biomarkers to improve OP and FM …

In both men and women around the world, lung cancer accounts as the principal cause of
cancer-related death after breast cancer. Therefore, early detection of the disease is a …

The extracellular matrix (ECM) affects cell behaviors, such as survival, proliferation, motility,
invasion, and differentiation. The arginine-glycine-aspartic acid (RGD) sequence is present …

Epigenetic variations can play remarkable roles in different normal and abnormal situations.
Such variations have been shown to have a direct role in the pathogenesis of various …