Effects of open-label placebos in clinical trials: a systematic review and meta-analysis

M von Wernsdorff, M Loef, B Tuschen-Caffier… - Scientific reports, 2021 - nature.com
Open-label placebos (OLPs) are placebos without deception in the sense that patients know
that they are receiving a placebo. The objective of our study is to systematically review and …

The ethics of placebo effects in clinical practice and research

M Annoni - International Review of Neurobiology, 2018 - Elsevier
This chapter provides a synthetic overview of the contemporary debate over the ethics of
placebos and placebo effects in both clinical and research contexts. Section 1 briefly …

Are open‐label placebos ethical? Informed consent and ethical equivocations

C Blease, L Colloca, TJ Kaptchuk - Bioethics, 2016 - Wiley Online Library
The doctor‐patient relationship is built on an implicit covenant of trust, yet it was not until the
post‐World War Two era that respect for patient autonomy emerged as an article of …

Robot lies in health care: When is deception morally permissible?

A Matthias - Kennedy Institute of Ethics Journal, 2015 - muse.jhu.edu
Autonomous robots are increasingly interacting with users who have limited knowledge of
robotics and are likely to have an erroneous mental model of the robot's workings …

If only they knew! A non‐inferiority randomized controlled trial comparing deceptive and open‐label placebo in healthy individuals

L Druart, SE Graham Longsworth… - … Journal of Pain, 2024 - Wiley Online Library
Background Placebo use is widespread in clinical practice. However, they are most often
administered deceptively rather than openly. It is often suggested that open‐label placebos …

The moral case for the clinical placebo

A Gold, P Lichtenberg - Journal of Medical Ethics, 2014 - jme.bmj.com
Placebos are arguably the most commonly prescribed drug, across cultures and throughout
history. Nevertheless, today many would consider their use in the clinic unethical, since …

The unfinished business of respect for autonomy: Persons, relationships, and nonhuman animals

RL Walker - The Journal of Medicine and Philosophy: A Forum …, 2020 - academic.oup.com
This essay explores three issues in respect for autonomy that pose unfinished business for
the concept. By this, I mean that the dialogue over them is ongoing and essentially …

Neurofeedback as placebo: a case of unintentional deception?

L Kalokairinou, LS Sullivan, A Wexler - Journal of medical ethics, 2022 - jme.bmj.com
The use of placebo in clinical practice has been the topic of extensive debate in the
bioethics literature, with much scholarship focusing on concerns regarding deception. While …

Placebos as a source of agency: evidence and implications

P Friesen - Frontiers in Psychiatry, 2019 - frontiersin.org
Bioethical discussions surrounding the use of placebos in clinical practice have long
revolved around the moral permissibility of deceiving a patient if it is likely to benefit them …

CAM-Präparate als therapeutische Placebos: wissenschaftstheoretische und medizinethische Überlegungen

B Schöne-Seifert, DR Friedrich, JO Reichardt - Zeitschrift für Evidenz …, 2015 - Elsevier
Zusammenfassung Die ‚Integration 'von CAM-Interventionen durch die Konventionelle
Medizin ist gegenwärtig in Deutschland wie in anderen Ländern ein ebenso reales wie …