The initial increases in force production with resistance training are thought to be primarily
underpinned by neural adaptations. This notion is firmly supported by evidence displaying …

After spinal cord injury (SCI), the destruction of spinal parenchyma causes permanent
deficits in motor functions, which correlates with the severity and location of the lesion …

Key points The ability to learn new motor skills is supported by plasticity in the structural and
functional organisation of the primary motor cortex in the human brain. Changes inhibitory to …

γ-Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the human brain
and can be measured with magnetic resonance spectroscopy (MRS). Conflicting accounts …

ABSTRACT N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamatergic
receptors that have been implicated in learning, development, and neuropathological …

The primary motor cortex (M1) is crucial for motor learning; however, its interaction with other
brain areas during motor learning remains unclear. We hypothesized that the fronto-parietal …

Since early days after stroke, the brain undergoes a complex reorganization to allow
compensatory mechanisms that promote functional recovery. However, these mechanisms …

Chronic low back pain (CLBP) is often associated with impaired control of deep trunk
muscles and reorganization of the primary motor areas (M1). Precisely, functional changes …

A deeper understanding of post-stroke plasticity is critical to devise more effective
pharmacological and rehabilitative treatments. The GABAergic system is one of the key …

Aerobic exercise can enhance neuroplasticity although presently the neural mechanisms
underpinning these benefits remain unclear. One possible mechanism is through effects on …