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The mediodorsal thalamus: an essential partner of the prefrontal cortex for cognition
S Parnaudeau, SS Bolkan, C Kellendonk - Biological psychiatry, 2018 - Elsevier
Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
Review of thalamocortical resting-state fMRI studies in schizophrenia
M Giraldo-Chica, ND Woodward - Schizophrenia research, 2017 - Elsevier
Brain circuitry underlying cognition, emotion, and perception is abnormal in schizophrenia.
There is considerable evidence that the neuropathology of schizophrenia includes the …
There is considerable evidence that the neuropathology of schizophrenia includes the …
[HTML][HTML] Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia
E Damaraju, EA Allen, A Belger, JM Ford, S McEwen… - NeuroImage: Clinical, 2014 - Elsevier
Schizophrenia is a psychotic disorder characterized by functional dysconnectivity or
abnormal integration between distant brain regions. Recent functional imaging studies have …
abnormal integration between distant brain regions. Recent functional imaging studies have …
Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness
A Anticevic, MW Cole, G Repovs, JD Murray… - Cerebral …, 2014 - academic.oup.com
Schizophrenia is a devastating neuropsychiatric syndrome associated with distributed brain
dysconnectivity that may involve large-scale thalamo-cortical systems. Incomplete …
dysconnectivity that may involve large-scale thalamo-cortical systems. Incomplete …
Thalamocortical organoids enable in vitro modeling of 22q11. 2 microdeletion associated with neuropsychiatric disorders
Thalamic dysfunction has been implicated in multiple psychiatric disorders. We sought to
study the mechanisms by which abnormalities emerge in the context of the 22q11. 2 …
study the mechanisms by which abnormalities emerge in the context of the 22q11. 2 …
Thalamocortical dysconnectivity in schizophrenia
ND Woodward, H Karbasforoushan… - American Journal of …, 2012 - psychiatryonline.org
Objective The thalamus and cerebral cortex are connected via topographically organized,
reciprocal connections. Previous studies have revealed thalamic abnormalities in …
reciprocal connections. Previous studies have revealed thalamic abnormalities in …
Prefrontal-thalamic anatomical connectivity and executive cognitive function in schizophrenia
M Giraldo-Chica, BP Rogers, SM Damon… - Biological …, 2018 - Elsevier
Background Executive cognitive functions, including working memory, cognitive flexibility,
and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated …
and inhibition, are impaired in schizophrenia. Executive functions rely on coordinated …
Inhibition of mediodorsal thalamus disrupts thalamofrontal connectivity and cognition
S Parnaudeau, PK O'neill, SS Bolkan, RD Ward… - Neuron, 2013 - cell.com
Cognitive deficits are central to schizophrenia, but the underlying mechanisms still remain
unclear. Imaging studies performed in patients point to decreased activity in the mediodorsal …
unclear. Imaging studies performed in patients point to decreased activity in the mediodorsal …
Map** thalamocortical functional connectivity in chronic and early stages of psychotic disorders
ND Woodward, S Heckers - Biological psychiatry, 2016 - Elsevier
Background There is considerable evidence that the thalamus is abnormal in psychotic
disorders. Resting-state functional magnetic resonance imaging has revealed an intriguing …
disorders. Resting-state functional magnetic resonance imaging has revealed an intriguing …
Brain-wide analysis of functional connectivity in first-episode and chronic stages of schizophrenia
Published reports of functional abnormalities in schizophrenia remain divergent due to lack
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …