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Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Controlled drug delivery vehicles for cancer treatment and their performance
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …
Bioresponsive materials
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …
pathological abnormalities, and interact with or are actuated by them, are appealing …
Aptamer/AuNP biosensor for colorimetric profiling of exosomal proteins
Exosomes constitute an emerging biomarker for cancer diagnosis because they carry
multiple proteins that reflect the origins of parent cells. Assessing exosome surface proteins …
multiple proteins that reflect the origins of parent cells. Assessing exosome surface proteins …
Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …
nanosystems holds great promise for biotechnological and biomedical applications. As a …
Transformable liquid-metal nanomedicine
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
Rational design of polymeric micelles for targeted therapeutic delivery
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
ATP-triggered anticancer drug delivery
Stimuli-triggered drug delivery systems have been increasingly used to promote
physiological specificity and on-demand therapeutic efficacy of anticancer drugs. Here we …
physiological specificity and on-demand therapeutic efficacy of anticancer drugs. Here we …
[HTML][HTML] Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery
Cancer-associated stimuli-responsive nanosystems have been increasingly considered for
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …
DNA-based nanostructures for live-cell analysis
DNA-based probes constitute a versatile platform for making biological measurements due
to their ability to recognize both nucleic acid and non-nucleic acid targets, ease of synthesis …
to their ability to recognize both nucleic acid and non-nucleic acid targets, ease of synthesis …