Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Exosomes constitute an emerging biomarker for cancer diagnosis because they carry
multiple proteins that reflect the origins of parent cells. Assessing exosome surface proteins …

The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Stimuli-triggered drug delivery systems have been increasingly used to promote
physiological specificity and on-demand therapeutic efficacy of anticancer drugs. Here we …

Cancer-associated stimuli-responsive nanosystems have been increasingly considered for
the delivery of anticancer drugs, which primarily target the tumor microenvironment and/or …

Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

DNA-based probes constitute a versatile platform for making biological measurements due
to their ability to recognize both nucleic acid and non-nucleic acid targets, ease of synthesis …