Evolution and diversity of assembly-line polyketide synthases: focus review

A Nivina, KP Yuet, J Hsu, C Khosla - Chemical reviews, 2019 - ACS Publications
Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …

Cytochrome P450 enzymes in fungal natural product biosynthesis

X Zhang, J Guo, F Cheng, S Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2015 to the end of 2020 Fungal-derived polyketides, non-ribosomal peptides,
terpenoids and their hybrids contribute significantly to the chemical space of total natural …

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

ST Cole, R Brosch, J Parkhill, T Garnier, C Churcher… - Nature, 1998 - nature.com
As a result of an error during film output, Table 1 was published with some symbols missing.
The correct version can be found at http://www. sanger. ac. uk and is reproduced again here …

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

SD Bentley, KF Chater, AM Cerdeño-Tárraga… - nature, 2002 - nature.com
Streptomyces coelicolor is a representative of the group of soil-dwelling, filamentous
bacteria responsible for producing most natural antibiotics used in human and veterinary …

The biosynthetic logic of polyketide diversity

C Hertweck - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Abstract Molecular Lego: Polyketides represent a highly diverse group of natural products
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …

[ΒΙΒΛΙΟ][B] Lichen biology

TH Nash - 1996 - books.google.com
Lichens are prominent examples of symbiotic organisms, combining fungi and algae and/or
cyanobacteria in an intimate biological union. This volume provides an up-to-date account of …

The influence of natural products upon drug discovery

DJ Newman, GM Cragg, KM Snader - Natural product reports, 2000 - pubs.rsc.org
3 Role of natural products in treatment of diseases 4 Antiinfective agents (including
antimalarials) 4.1 Antibacterials: b-lactams 4.2 Antibacterials: aminoglycosides 4.3 …

Polyketide biosynthesis: a millennium review

J Staunton, KJ Weissman - Natural product reports, 2001 - pubs.rsc.org
Polyketide biosynthesis: a millennium review - Natural Product Reports (RSC Publishing)
DOI:10.1039/A909079G Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article …

Phthalides and phthalans: synthetic methodologies and their applications in the total synthesis

R Karmakar, P Pahari, D Mal - Chemical reviews, 2014 - ACS Publications
Small molecule natural products have been the mainstay of research in organic chemistry
since its early development. 1a The established classes of natural products, like alkaloids …

Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms

MA Fischbach, CT Walsh - Chemical reviews, 2006 - ACS Publications
Many thousands of small molecule natural products with interesting biological activities are
polyketides (PK), nonribosomal peptides (NRP), or hybrids thereof (ie, PK-NRP hybrids) …