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Chemopreventive properties of 3, 3′-diindolylmethane in breast cancer: evidence from experimental and human studies
Diet is a modifiable factor associated with the risk of several cancers, with convincing
evidence showing a link between diet and breast cancer. The role of bioactive compounds …
evidence showing a link between diet and breast cancer. The role of bioactive compounds …
Indole derivatives as anticancer agents for breast cancer therapy: a review
Breast cancer (BC) is the second most common cause of cancer-related deaths in women
throughout the world. Multiple drugs have been approved by US-FDA for breast related …
throughout the world. Multiple drugs have been approved by US-FDA for breast related …
Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer …
C Qu, W Zhang, G Zheng, Z Zhang, J Yin… - Molecular and cellular …, 2014 - Springer
Breast cancer is the most frequently diagnosed tumor type and the primary leading cause of
cancer deaths in women worldwide and multidrug resistance is the major obstacle for breast …
cancer deaths in women worldwide and multidrug resistance is the major obstacle for breast …
[HTML][HTML] Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity
In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives
containing Schiff base moieties were prepared and screened for their antibacterial activity …
containing Schiff base moieties were prepared and screened for their antibacterial activity …
The DEAD box protein p68: a crucial regulator of AKT/FOXO3a signaling axis in oncogenesis
Increased abundance of proto-oncogene AKT and reduced expression of tumor suppressor
Forkhead box O3 (FOXO3a), the downstream target of AKT, is frequent in carcinogenesis …
Forkhead box O3 (FOXO3a), the downstream target of AKT, is frequent in carcinogenesis …
HAUSP, a novel deubiquitinase for Rb–MDM 2 the critical regulator
Tumor suppressor retinoblastoma‐associated protein (Rb) is an important cell cycle
regulator, arresting cells in early G1. It is commonly inactivated in cancers and its level is …
regulator, arresting cells in early G1. It is commonly inactivated in cancers and its level is …
Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin
Q Chen, YQ Meng, XF Xu, J Gu - Anti-Cancer Drugs, 2017 - journals.lww.com
The tolerance to adriamycin of cancer as a common and stubborn obstacle occurred during
curing breast cancer patients needs to be overcome. In the present study, we explored …
curing breast cancer patients needs to be overcome. In the present study, we explored …
[HTML][HTML] Wnt/β-catenin signaling and p68 conjointly regulate CHIP in colorectal carcinoma
Emerging evidences suggest abundant expression of Carboxy terminus of Hsc70 Interacting
Protein or CHIP (alias STIP1 Homology and U–box Containing Protein 1 or STUB1) in …
Protein or CHIP (alias STIP1 Homology and U–box Containing Protein 1 or STUB1) in …
DEAD-box protein p68 is regulated by β-catenin/transcription factor 4 to maintain a positive feedback loop in control of breast cancer progression
KKN Guturi, M Sarkar, A Bhowmik, N Das… - Breast Cancer …, 2014 - Springer
Introduction Nuclear accumulation of β-catenin is important for cancer development and it is
found to overlap with p68 (DDX5) immunoreactivity in most breast cancers, as indicated by …
found to overlap with p68 (DDX5) immunoreactivity in most breast cancers, as indicated by …
Anti-SSTR2 peptide based targeted delivery of potent PLGA encapsulated 3, 3'-diindolylmethane nanoparticles through blood brain barrier prevents glioma …
A Bhowmik, S Chakravarti, A Ghosh, R Shaw… - …, 2017 - pmc.ncbi.nlm.nih.gov
Current therapy for Glioblastoma is insufficient because of the presence of blood brain
barrier. It limits the transport of essential drugs to the tumor sites. To overcome this limitation …
barrier. It limits the transport of essential drugs to the tumor sites. To overcome this limitation …