Form follows function: nanoparticle shape and its implications for nanomedicine

C Kinnear, TL Moore, L Rodriguez-Lorenzo… - Chemical …, 2017 - ACS Publications
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …

The importance of nanoparticle shape in cancer drug delivery

NP Truong, MR Whittaker, CW Mak… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Nanoparticles have been successfully used for cancer drug delivery since
1995. In the design of commercial nanoparticles, size and surface characteristics have been …

Nanocarriers as potential drug delivery candidates for overcoming the blood–brain barrier: challenges and possibilities

J Ahlawat, G Guillama Barroso, S Masoudi Asil… - Acs Omega, 2020 - ACS Publications
The design of a drug that successfully overcomes the constraints imposed by the blood–
brain barrier (BBB, which acts as a gatekeeper to the entry of substances into the brain) …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
Many types of research have distinctly addressed the efficacy of natural plant metabolites
used for human consumption both in cell culture and preclinical animal model systems …

Sha** Cancer Nanomedicine: The Effect of Particle Shape on The In Vivo Journey of Nanoparticles

R Toy, PM Peiris, KB Ghaghada, E Karathanasis - Nanomedicine, 2014 - Taylor & Francis
Recent advances in nanoparticle technology have enabled the fabrication of nanoparticle
classes with unique sizes, shapes and materials, which in turn has facilitated major …

Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Anisotropic nanomaterials for shape-dependent physicochemical and biomedical applications

L Yang, Z Zhou, J Song, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
This review contributes towards a systematic understanding of the mechanism of shape-
dependent effects on nanoparticles (NPs) for elaborating and predicting their properties and …

The impact of aspect ratio on the biodistribution and tumor homing of rigid soft‐matter nanorods

S Shukla, FJ Eber, AS Nagarajan… - Advanced …, 2015 - Wiley Online Library
The size and shape of nanocarriers can affect their fate in vivo, but little is known about the
effect of nanocarrier aspect ratio on biodistribution in the setting of cancer imaging and drug …

[HTML][HTML] Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and-spheres in mice

MA Bruckman, LN Randolph, A VanMeter, S Hern… - Virology, 2014 - Elsevier
Understanding the pharmacokinetics, blood compatibility, biodistribution and clearance
properties of nanoparticles is of great importance to their translation to clinical application. In …

Virus-based nanoparticles as versatile nanomachines

KJ Koudelka, AS Pitek, M Manchester… - Annual review of …, 2015 - annualreviews.org
Nanoscale engineering is revolutionizing the way we prevent, detect, and treat diseases.
Viruses have played a special role in these developments because they can function as …