Allogeneic haematopoietic stem cell transplantation is used to treat a variety of disorders,
but its efficacy is limited by the occurrence of graft-versus-host disease (GVHD). The past …

Haemopoietic-cell transplantation (HCT) is an intensive therapy used to treat high-risk
haematological malignant disorders and other life-threatening haematological and genetic …

Graft-versus-host disease (GVHD) in the gastrointestinal (GI) tract is the principal
determinant of lethality following allogeneic bone marrow transplantation (BMT). Here, we …

For over 60 years, hematopoietic stem cell transplantation has been the major curative
therapy for several hematological and genetic disorders, but its efficacy is limited by the …

Mature donor T cells cause graft-versus-host disease (GVHD), but they are also the main
mediators of the beneficial graft-versus-tumor (GVT) activity of allogeneic bone marrow …

Mesenchymal stem cells (MSCs) have fueled ample translation for the treatment of immune‐
mediated diseases. They exert immunoregulatory and tissue‐restoring effects. MSC …

Allogeneic haematopoietic stem-cell transplantation (SCT) is a curative therapy for
haematological malignancies and inherited disorders of blood cells, such as sickle-cell …

Allogeneic transplantation of hematopoietic cells is an effective treatment of leukemia, even
in advanced stages. Allogeneic lymphocytes produce a strong graft-versus-leukemia (GVL) …

Allogeneic hematopoietic stem cell transplantation (SCT) is a curative therapy for various
hematologic disorders. Graft-versus-host disease (GVHD) and infections are the major …

The limiting factor for successful hematopoietic stem cell transplantation (HSCT) is graft-
versus-host disease (GvHD), a post-transplant disorder that results from immune-mediated …