Some remarks on protein attribute prediction and pseudo amino acid composition
KC Chou - Journal of theoretical biology, 2011 - Elsevier
With the accomplishment of human genome sequencing, the number of sequence-known
proteins has increased explosively. In contrast, the pace is much slower in determining their …
proteins has increased explosively. In contrast, the pace is much slower in determining their …
Impacts of bioinformatics to medicinal chemistry
KC Chou - Medicinal chemistry, 2015 - ingentaconnect.com
Facing the explosive growth of biological sequence data, such as those of protein/peptide
and DNA/RNA, generated in the post-genomic age, many bioinformatical and mathematical …
and DNA/RNA, generated in the post-genomic age, many bioinformatical and mathematical …
iRSpot-PseDNC: identify recombination spots with pseudo dinucleotide composition
Meiotic recombination is an important biological process. As a main driving force of
evolution, recombination provides natural new combinations of genetic variations. Rather …
evolution, recombination provides natural new combinations of genetic variations. Rather …
iPromoter-2L: a two-layer predictor for identifying promoters and their types by multi-window-based PseKNC
B Liu, F Yang, DS Huang, KC Chou - Bioinformatics, 2018 - academic.oup.com
Motivation Being responsible for initiating transaction of a particular gene in genome,
promoter is a short region of DNA. Promoters have various types with different functions …
promoter is a short region of DNA. Promoters have various types with different functions …
[HTML][HTML] iDNA6mA-PseKNC: Identifying DNA N6-methyladenosine sites by incorporating nucleotide physicochemical properties into PseKNC
Abstract N 6-methyladenine (6mA) is one kind of post-replication modification (PTM or
PTRM) occurring in a wide range of DNA sequences. Accurate identification of its sites will …
PTRM) occurring in a wide range of DNA sequences. Accurate identification of its sites will …
iAMP-2L: a two-level multi-label classifier for identifying antimicrobial peptides and their functional types
Antimicrobial peptides (AMPs), also called host defense peptides, are an evolutionarily
conserved component of the innate immune response and are found among all classes of …
conserved component of the innate immune response and are found among all classes of …
PseKNC: a flexible web server for generating pseudo K-tuple nucleotide composition
The pseudo oligonucleotide composition, or pseudo K-tuple nucleotide composition
(PseKNC), can be used to represent a DNA or RNA sequence with a discrete model or …
(PseKNC), can be used to represent a DNA or RNA sequence with a discrete model or …
Pseudo amino acid composition and its applications in bioinformatics, proteomics and system biology
KC Chou - Current Proteomics, 2009 - ingentaconnect.com
With the avalanche of protein sequences generated in the post-genomic age, it is highly
desired to develop automated methods for efficiently identifying various attributes of …
desired to develop automated methods for efficiently identifying various attributes of …
iNuc-PseKNC: a sequence-based predictor for predicting nucleosome positioning in genomes with pseudo k-tuple nucleotide composition
Motivation: Nucleosome positioning participates in many cellular activities and plays
significant roles in regulating cellular processes. With the avalanche of genome sequences …
significant roles in regulating cellular processes. With the avalanche of genome sequences …
iRNA (m6A)-PseDNC: identifying N6-methyladenosine sites using pseudo dinucleotide composition
As a prevalent post-transcriptional modification, N 6-methyladenosine (m 6 A) plays key
roles in a series of biological processes. Although experimental technologies have been …
roles in a series of biological processes. Although experimental technologies have been …