Selective hydrogenation for fine chemicals: recent trends and new developments

HU Blaser, C Malan, B Pugin, F Spindler… - … synthesis & catalysis, 2003 - Wiley Online Library
In this overview, recent trends and developments for the selective hydrogenation of
multifunctional molecules are discussed and assessed from the point of view of fine …

Microwave‐Assisted Paal–Knorr Reaction–Three‐Step Regiocontrolled Synthesis of Polysubstituted Furans, Pyrroles and Thiophenes

G Minetto, LF Raveglia, A Sega, M Taddei - 2005 - Wiley Online Library
An efficient and highly versatile synthesis of furans, pyrroles and thiophenes is described.
Starting from commercially available or easily prepared β‐keto esters, functional …

Pd/C catalysis under microwave dielectric heating

E Cini, E Petricci, M Taddei - Catalysts, 2017 - mdpi.com
Microwave-assisted organic synthesis (MAOS) provides a novel and efficient means of
achieving heat organic reactions. Nevertheless, the potential arcing phenomena via …

Novel imidazo [4, 5-b] pyridine derived acrylonitriles: A combined experimental and computational study of their antioxidative potential

I Boček, K Starčević, IN Jovanović, R Vianello… - Journal of molecular …, 2021 - Elsevier
We describe the synthesis of novel unsubstituted and N-substituted imidazo [4, 5-b] pyridine
derived acrylonitriles, which were prepared by classical and microwave assisted organic …

Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity

A Solinas, H Faure, H Roudaut, E Traiffort… - Journal of medicinal …, 2012 - ACS Publications
The Smoothened (Smo) receptor is the major transducer of the Hedgehog (Hh) signaling
pathway. On the basis of the structure of the acylthiourea Smo antagonist (MRT-10), a …

Dual-targeting peptides@ PMO, a mimetic to the pro-apoptotic protein Smac/DIABLO for selective activation of apoptosis in cancer cells

E Di Giorgio, A Ferino, W Huang, S Simonetti… - Frontiers in …, 2023 - frontiersin.org
The refractoriness of tumor cells to apoptosis represents the main mechanism of resistance
to chemotherapy. Smac/DIABLO mimetics proved to be effective in overcoming cancer …

Insights into the aggregation-induced emission of 1, 8-naphthalimide-based supramolecular hydrogels

C Felip-León, F Galindo, JF Miravet - Nanoscale, 2018 - pubs.rsc.org
The study of aggregation-induced emission (AIE) of a series of 1, 8-naphthalimide
derivatives in aqueous media is reported herein. Some of these molecules constitute the first …

Mild Method for Deprotection of the N-Benzyloxycarbonyl (N-Cbz) Group by the Combination of AlCl3 and HFIP

V Vinayagam, SK Sadhukhan, DV Botla… - The Journal of …, 2024 - ACS Publications
Herein, we report our findings on the novel ability of aluminum chloride (AlCl3) in fluorinated
solvent 1, 1, 1, 3, 3, 3-hexafluoroisopropanol [HFIP] to selectively deprotect the N …

Kolbe anodic decarboxylation as a green way to access 2-pyrrolidinones

M Quertenmont, I Goodall, K Lam, I Markó… - Organic letters, 2020 - ACS Publications
Nootropic compounds are a group of pharmacologically active pyrrolidones. These
molecules, which enhance cognition properties and possess a large prescription field, are …

Diversity-oriented synthesis of cyclic acyldepsipeptides leads to the discovery of a potent antibacterial agent

AM Socha, NY Tan, KL LaPlante, JK Sello - Bioorganic & medicinal …, 2010 - Elsevier
A class of cyclic acyldepsipeptide antibiotics collectively known as the enopeptins has
recently attracted much attention because of their activity against multidrug-resistant …