Digital twins for multiple sclerosis

I Voigt, H Inojosa, A Dillenseger, R Haase… - Frontiers in …, 2021 - frontiersin.org
An individualized innovative disease management is of great importance for people with
multiple sclerosis (pwMS) to cope with the complexity of this chronic, multidimensional …

Digital biomarkers in multiple sclerosis

A Dillenseger, ML Weidemann, K Trentzsch, H Inojosa… - Brain sciences, 2021 - mdpi.com
For incurable diseases, such as multiple sclerosis (MS), the prevention of progression and
the preservation of quality of life play a crucial role over the entire therapy period. In MS …

Patient-reported outcomes in multiple sclerosis care

E D'Amico, R Haase, T Ziemssen - Multiple sclerosis and related disorders, 2019 - Elsevier
Patient-reported outcomes (PROs) are increasingly used in multiple sclerosis (MS) research
and clinical practice for understanding the effects that the disease and its treatments have on …

Profiling individual clinical responses by high-frequency serum neurofilament assessment in MS

K Akgün, N Kretschmann, R Haase… - Neurology …, 2019 - AAN Enterprises
Objective To evaluate individual neurofilament light chain (NfL) variation over the time of
disease course and the potential of NfL measurement to predict treatment response in …

Multiple sclerosis registries in Europe–an updated map** survey

A Glaser, A Stahmann, T Meissner… - Multiple sclerosis and …, 2019 - Elsevier
Author links open overlay panel A. Glaser a, A. Stahmann b, T. Meissner c, P. Flachenecker
d, D. Horáková e, P. Zaratin fg, G. Brichetto gh, M. Pugliatti ij, O. Rienhoff c, S. Vukusic klmn …

Electronic health interventions in the case of multiple sclerosis: from theory to practice

M Scholz, R Haase, D Schriefer, I Voigt, T Ziemssen - Brain Sciences, 2021 - mdpi.com
(1) Background: eHealth interventions play a growing role in sha** the future healthcare
system. The integration of eHealth interventions can enhance the efficiency and quality of …

A digital patient portal for patients with multiple sclerosis

I Voigt, M Benedict, M Susky, T Scheplitz… - Frontiers in …, 2020 - frontiersin.org
Background: Multiple Sclerosis is a chronic inflammatory disease of the central nervous
system that requires a complex, differential, and lifelong treatment strategy, which involves …

Real world lab data: patterns of lymphocyte counts in fingolimod treated patients

M Kaufmann, R Haase, U Proschmann… - Frontiers in …, 2018 - frontiersin.org
Objective: Fingolimod is approved for the treatment of highly active relapsing remitting
multiple sclerosis (MS) patients and acts by its unique mechanism of action via sphingosine …

Long-term real-world effectiveness and safety of fingolimod over 5 years in Germany

T Ziemssen, M Lang, S Schmidt, H Albrecht, L Klotz… - Journal of …, 2022 - Springer
Objective To evaluate the 5-year real-world benefit–risk profile of fingolimod in patients with
relapsing–remitting MS (RRMS) in Germany. Methods Post-Authorization Non-interventional …

Data collection in multiple sclerosis: the MSDS approach

T Ziemssen, R Kern, I Voigt, R Haase - Frontiers in Neurology, 2020 - frontiersin.org
Multiple sclerosis (MS) is a frequent chronic inflammatory disease of the central nervous
system that affects patients over decades. As the monitoring and treatment of MS become …