Genetic marker discovery in complex traits: a field example on fat content and composition in pigs

RN Pena, R Ros-Freixedes, M Tor, J Estany - International Journal of …, 2016 - mdpi.com
Among the large number of attributes that define pork quality, fat content and composition
have attracted the attention of breeders in the recent years due to their interaction with …

Association of twelve candidate gene polymorphisms with the intramuscular fat content and average backfat thickness of Chinese Suhuai pigs

B Wang, P Li, W Zhou, C Gao, H Liu, H Li, P Niu… - Animals, 2019 - mdpi.com
Simple Summary Appropriate intramuscular fat content (IFC) is the goal of consumers and
the direction that breeders must pursue. However, it is difficult to improve the IFC but not …

Genomics of heat tolerance in reproductive performance investigated in four independent maternal lines of pigs

F Tiezzi, LF Brito, J Howard, YJ Huang, K Gray… - Frontiers in …, 2020 - frontiersin.org
Improving swine climatic resilience through genomic selection has the potential to minimize
welfare issues and increase the industry profitability. The main objective of this study was to …

Bioinformatic approach to identifying causative missense polymorphisms in animal genomes

M Peka, V Balatsky - BMC genomics, 2024 - Springer
Background Trends in the development of genetic markers for the purposes of genomic and
marker-assisted selection primarily focus on identifying causative polymorphisms. Using …

The Asp298Asn polymorphism of melanocortin‐4 receptor (MC4R) in pigs: evidence for its potential effects on MC4R constitutive activity and cell surface expression

J Zhang, J Li, C Wu, Z Hu, L An, Y Wan, C Fang… - Animal …, 2020 - Wiley Online Library
In humans and mice, melanocortin receptor 4 (MC4R) and melanocortin receptor accessory
protein 2 (MRAP2) can form a complex and control energy balance, thus regulating body …

Trait correlated expression combined with eQTL and ASE analyses identified novel candidate genes affecting intramuscular fat

Y Liu, H Long, S Feng, T Ma, M Wang, L Niu, X Zhang… - BMC genomics, 2021 - Springer
Background Intramuscular fat (IMF) content is a determining factor for meat taste. The
Luchuan pig is a fat-type local breed in southern China that is famous for its desirable meat …

Genomic background of biotypes related to growth, carcass and meat quality traits in Duroc pigs based on principal component analysis

HE Green, HR Oliveira, AB Alvarenga… - Journal of Animal …, 2024 - Wiley Online Library
As the swine industry continues to explore pork quality traits alongside growth, feed
efficiency and carcass leanness traits, it becomes imperative to understand their underlying …

[HTML][HTML] A Critical Functional Missense Mutation (T117M) in Sheep MC4R Gene Significantly Leads to Gain-of-Function

Z Zhao, Y Yang, P Liu, T Yan, R Li, C Pan, Y Li, X Lan - Animals, 2024 - mdpi.com
Simple Summary The melanocortin 4 receptor (MC4R) is an important gene that can affect
the growth and economic traits of sheep. This study first investigated the distribution of the …

Potential of eight mutations for marker-assisted breeding in Chinese Lulai black pigs

J Xu, A Jiang, C Zhang, Y Zheng… - Canadian Journal of …, 2022 - cdnsciencepub.com
Molecular marker-assisted selection (MAS) provides an efficient tool for pig breeding. In this
study, according to the literature, we selected eight effective or causal mutations from eight …

Profiling and functional analysis of long noncoding RNAs and mRNAs during porcine skeletal muscle development

Y Tan, M Gan, L Shen, L Li, Y Fan, Y Chen… - International Journal of …, 2021 - mdpi.com
Gene transcripts or mRNAs and long noncoding RNAs (lncRNAs) are differentially
expressed during porcine skeletal muscle development. However, only a few studies have …