Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

Renal ischemia-reperfusion leads to acute kidney injury (AKI), a major kidney disease
associated with an increasing prevalence and high mortality rates. A variety of experimental …

Rhabdomyolysis-induced acute kidney injury (RIAKI) occurs following damage to the
muscular sarcolemma sheath, resulting in the leakage of myoglobin and other metabolites …

Alcoholic liver disease (ALD) accounts for a large fraction of patients with cirrhosis and
hepatocellular carcinoma. In the present study we investigated the involvement of Brahma …

NK cells are innate lymphoid cells important for immune surveillance, identifying and
responding to stress, infection, and/or transformation. Whereas conventional NK (cNK) cells …

Abstract Ischemia/reperfusion injury (IRI), an inherent component of transplantation, affects
organ quality and transplant outcomes. Although the complexity of the pathophysiology is …

The possible therapeutic benefits of B-cell depletion in combating tumoral immune escape
have been debated. In support of this concept, metastasis of highly aggressive 4T1 breast …

Tissue-resident immune cells reside in distinct niches across organs, where they contribute
to tissue homeostasis and rapidly respond to perturbations in the local microenvironment …

Cardiomyocyte apoptosis in response to inflammation is a primary cause of myocardial
ischemia-reperfusion injury (IRI). Nuclear factor erythroid 2 like 2 (Nrf2) reportedly plays an …

Natural killer (NK) cells are a population of lymphoid cells that play a significant role in
mediating innate immune responses. Studies in mice suggest a pathological role for NK …