The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections

ED Karousis - Biochemical Society Transactions, 2024 - portlandpress.com
Non-structural protein 1 (Nsp1) is one of the first proteins produced during coronaviral
infections. It plays a pivotal role in hijacking and rendering the host gene expression under …

SARS-CoV-2 Nsp1 traps RNA in the nucleus to escape immune detection

JV Guillen, BA Glaunsinger - Proceedings of the National Academy of …, 2024 - pnas.org
The battle for control of gene expression is central to the outcome of a virus–host interaction.
On the cellular side, mounting an effective innate immune response to infection requires …

[HTML][HTML] Betacoronaviruses Differentially Activate the Integrated Stress Response to Optimize Viral Replication in Lung-Derived Cell Lines

DM Renner, NA Parenti, N Bracci, SR Weiss - Viruses, 2025 - mdpi.com
The betacoronavirus genus contains five of the seven human coronaviruses, making it a
particularly critical area of research to prepare for future viral emergence. We utilized three …

[HTML][HTML] 4D-DIA-Based Quantitative Proteomic Analysis Reveals the Involvement of TRPV2 Protein in Duck Tembusu Virus Replication

J Chen, F Yang, L Lai, H Li, C Pan, X Bao, W Lin, R Lin - Viruses, 2024 - mdpi.com
Duck Tembusu virus (DTMUV), a novel positive-sense RNA virus, has caused significant
economic losses in the poultry industry of Eastern and Southeast Asia since its outbreak in …

The transcriptional and translational landscape of HCoV-OC43 infection

S Bresson, E Sani, A Armatowska, C Dixon… - PLoS …, 2025 - journals.plos.org
The coronavirus HCoV-OC43 circulates continuously in the human population and is a
frequent cause of the common cold. Here, we generated a high-resolution atlas of the …