Iron is essential for the survival of most bacteria but presents a significant challenge given its
limited bioavailability. Furthermore, the toxicity of iron combined with the need to maintain …

Recent breakthroughs in highly accurate protein structure prediction using deep neural
networks have made considerable progress in solving the structure prediction component of …

Iron is an important micronutrient that is required by bacteria to proliferate and to cause
disease. Many bacterial pathogens forage iron from human hemoglobin (Hb) during …

Staphylococcus aureus is a versatile opportunistic human pathogen. Infection by this
bacterium requires uptake of iron from the human host, but iron is highly restricted in this …

The present study investigates the interactions between eight glucosinolate hydrolysis
products (GHPs) sourced from broccoli by-products and the detoxifying enzymes of Botrytis …

Staphylococcus aureus is a major cause of deadly nosocomial infections, a severe problem
fueled by the steady increase of resistant bacteria. The iron surface determinant (Isd) system …

HtaA is a heme-binding protein that is part of the heme uptake system in Corynebacterium
diphtheriae. HtaA contains two conserved regions (CR1 and CR2). It has been previously …

In order to proliferate and mount an infection, many bacterial pathogens need to acquire iron
from their host. The most abundant iron source in the body is the oxygen transporter …

Cyanobacteria can produce alkanes equivalent to diesel fuels through a two-step enzymatic
process involving acyl-(acyl carrier protein) reductase (AAR) and aldehyde deformylating …

The crystal structures of the conserved region domains of HtaA and HtaB, which act as heme
binding/transport proteins in the heme uptake machinery in Corynebacterium glutamicum …