Conspectus Lipid nanoparticles (LNPs) are a type of lipid vesicles that possess a
homogeneous lipid core. These vesicles are widely used in small-molecule drug and …

Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Lipid nanoparticle (LNP) packaged mRNA vaccines have been deployed against infectious
diseases such as COVID-19, yet their structural features remain unclear. Cholesterol, a …

The development of safe and efficacious gene vectors has limited greatly the potential for
therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) …

The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

The oligonucleotide therapeutics field has seen remarkable progress over the last few years
with the approval of the first antisense drug and with promising developments in late stage …

The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …

RNA therapeutics have the potential to resolve a myriad of genetic diseases. Lipid
nanoparticles (LNPs) are among the most successful RNA delivery systems. Expanding their …

Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …