Regulation of inflammation by the antioxidant haem oxygenase 1

NK Campbell, HK Fitzgerald, A Dunne - Nature Reviews Immunology, 2021 - nature.com
Abstract Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of
haem, is primarily considered an antioxidant, and has long been overlooked by …

Tolerogenic dendritic cells in solid organ transplantation: where do we stand?

E Marín, MC Cuturi, A Moreau - Frontiers in immunology, 2018 - frontiersin.org
Over the past century, solid organ transplantation has been improved both at a surgical and
postoperative level. However, despite the improvement in efficiency, safety, and survival, we …

Human tolerogenic dendritic cells regulate immune responses through lactate synthesis

E Marin, L Bouchet-Delbos, O Renoult, C Louvet… - Cell metabolism, 2019 - cell.com
Cell therapy is a promising strategy for treating patients suffering from autoimmune or
inflammatory diseases or receiving a transplant. Based on our preclinical studies, we have …

Tolerogenic dendritic cells and their role in transplantation

M Ezzelarab, AW Thomson - Seminars in immunology, 2011 - Elsevier
The pursuit of clinical transplant tolerance has led to enhanced understanding of
mechanisms underlying immune regulation, including the characterization of immune …

Update on dendritic cell-induced immunological and clinical tolerance

C Obregon, R Kumar, MA Pascual, G Vassalli… - Frontiers in …, 2017 - frontiersin.org
Dendritic cells (DCs) as highly efficient antigen-presenting cells are at the interface of innate
and adaptive immunity. As such, they are key mediators of immunity and antigen-specific …

A Phase I/IIa study of autologous tolerogenic dendritic cells immunotherapy in kidney transplant recipients

A Moreau, D Kervella, L Bouchet-Delbos… - Kidney International, 2023 - Elsevier
Kidney transplant survival is shortened by chronic rejection and side effects of standard
immunosuppressive drugs. Cell-based immunotherapy with tolerogenic dendritic cells has …

Tolerogenic dendritic cells in organ transplantation

J Ochando, F Ordikhani, S Jordan, P Boros… - Transplant …, 2020 - Wiley Online Library
Dendritic cells (DC s) are specialized cells of the innate immune system that are
characterized by their ability to take up, process and present antigens (Ag) to effector T cells …

Regulatory macrophages and tolerogenic dendritic cells in myeloid regulatory cell-based therapies

M Suuring, A Moreau - International journal of molecular sciences, 2021 - mdpi.com
Myeloid regulatory cell-based therapy has been shown to be a promising cell-based
medicinal approach in organ transplantation and for the treatment of autoimmune diseases …

The role of dendritic cells in the immunomodulation to implanted biomaterials

S Wang, Y Chen, Z Ling, J Li, J Hu, F He… - International Journal of …, 2022 - nature.com
Considering the substantial role played by dendritic cells (DCs) in the immune system to
bridge innate and adaptive immunity, studies on DC-mediated immunity toward biomaterials …

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

G Amodio, J Cichy, P Conde, G Matteoli… - Cancer Immunology …, 2019 - Springer
Myeloid cells play a pivotal role in regulating innate and adaptive immune responses. In
inflammation, autoimmunity, and after transplantation, myeloid cells have contrasting roles …